Hemwati Nandan Bahuguna Uttarakhand Medical Education University
Administrative Block, Govt. Doon Medical College Campus, Dehrakhas, Patel Nagar, Dehradun - 248001
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Phone: 0135 - 2723323 Fax: 0135 - 2723323Website: www.hnbumu.ac.in E-mail: info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject : Pathology Duration: 01:30 Hrs.
Date : 06.01.2020 Place : Dehradun
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Max Marks: 60Student Name: Invigilator Name:
Signature: Signature:
- Coagulative necrosis is:
- Characteristic of focal bacterial infections.
- Characteristic of hypoxic death.
- Characteristic by loss of tissue architecture.
- None of the above.
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- Dystrophic calcification are calcifications seen in:
- Skin layers
- Salivary glands
- Normal tissues
- Dead tissue
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- Diabetic gangrene is caused by:
- Vasospasm
- Peripheral neuritis
- Atherosclerosis
- None of the above
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- Liquefaction necrosis is commonly seen in:
- Brain
- Lung
- Liver
- Spleen
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- Stain used for demonstration of amyloid is:
- Congo red
- Masson’s trichrome
- Vonkosa
- Reticulin
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- Physiologic programmed cell death is termed as:
- Apoptosis
- Lysis
- Autolysis
- Autopsy
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- Amyloidosis is commonly-associated with:
- Chronic osteomyelitis
- Periostitis
- Acute osteomyelitis
- Multiple myeloma
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- Metastatic calcifications are seen in:
- Hypoparathyroidism
- Vitamin D deficiency
- Hypercalcemia
- All of the above
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- Which of the following is correctly matched
- Coagulation necrosis tuberculosis
- Caseation yellow fever
- Fat necrosis pancreatitis
- Gumma infarction
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- Cellular swelling and fatty change are example of :
- Reversible injury
- Irreversible injury
- Both a and b
- None of the above
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- Hypoxic death leads to:
- Liquefactive necrosis
- Coagulative necrosis
- Caseous necrosis
- Fat necrosis
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- Pyknosis is characterized by:
- Nuclear basophilia
- Nuclear shrinkage
- Nucleus disintegration
- Nucleolus disintegration
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- Which of the following is correct
- Pyknosis- shrinkage of nucleus
- Karyolysis- dissolution of nucleus
- Karyorrhexis- fragmentation of nucleus
- All of the above
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- Gangrene is the death of a part accompanied by:
- Suppuration
- Putrefaction
- Calcification
- Coagulation
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- The hormone dependent shedding of endometrium is an example of:
- Necrosis
- Autolysis
- Apoptosis
- None of the above
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- Mallory’s degeneration seen-in alcoholic liver disease is a form of:
- Hyaline degeneration
- Amyloid degeneration
- Hydropic degeneration
- Fatty degeneration
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- A reduction in the total leucocyte count is called:
- Leucocytosis
- Leucopenia
- Leucorrhoea
- Leukemia
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- Reduced number of platelet is found in all the conditions except:
- Disseminated intravascular coagulation.
- Aplastic anaemia
- Acute myelocytic leukemia
- Von willebrand disease
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- In hemophilic patient which of the following should not be given:
- Factor VIII concentrate
- Cryoprecipitate
- EACA
- Platelet factor
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- Normal adult haemoglobin contains:
- One alpha and one beta chain
- One alpha and two beta chains
- One beta chains and two alpha chains
- Two alpha chains and two beta chains
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- In megaloblastic anaemia the cells are:
- Macrocytic hyperchromic
- Macrocytic hypochromic
- Macroytic normochromic
- None of the above
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- Pernicious anaemia is associated with the deficiency of:
- Folic acid
- Vitamin B1
- Vitamin B6
- Vitamin B12
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- A patient reports with dyspnoea on slight exertion. He also has multiple spots and spontaneous hemorrhage. His RBC count is less than one lakh/mm3 his hematocrit and haemoglobin is low. Most probable diagnosis is:
- Pernicious anemia
- Thalassemia
- Aplastic anemia
- Sprue
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- A patient with a bleeding disorder with increased bleeding time and normal clotting time is suffering from:
- Classic haemophilia
- Christmas disease
- Vitamin K deficiency
- Idiopathic thrombocytopenic purpura
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- Gingivae are enlarged in leukemia because of:
- Capillary dilation
- Erythrocyte engorgement
- Edema
- WBC infiltration
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- Oedema may be caused by any of the following EXCEPT:
- An increase in the plasma protein concentration
- An increase in the capillary hydrostatic pressure
- An increase in the capillary permeability
- Lymphatic obstruction
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- The most common site of origin for venous thrombi leading to pulmonary embolism is:
- Ascending aorta
- Portal vein
- Deep leg veins
- Right atrium
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- Edema is due to:
- Increased albumin in blood and decreased globin
- Decreased albumin conc. in blood
- Increased osmotic pressure
- None of the above
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- Anasarca means:
- Abnormal inflammatory process
- Severe generalized swelling
- Absence of proliferation of vessels following inflammation
- Presence of pus
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- All of the following are typically associated with loss of 40% of the circulating blood volume except:
- A decrease in the blood pressure
- A decrease in the central venous pressure
- A decrease in the heart rate
- A decrease in the urine output
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- Which of the following is common in all forms of shock?
- Sepsis
- Hypovolemia
- Vasoconstriction
- Impaired tissue perfusion
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- In hypovolemic shock:
- The central venous pressure is high
- The extremities are pale, cold and sweating
- There is always a site of bleeding
- Urine output is unaffected
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- Shock is a circulatory disturbance characterized by:
- Increased blood pressure
- Decreased volume of circulation blood
- Elevated body temperature
- Decreased volume of interstitial fluid
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- Hypovolemic shock develops after loss of:
- 10% blood
- 20% blood
- 30% blood
- 40% blood
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- Following is the most important factor in the management of shock:
- Blood pressure
- Cardiac output
- CVP to 8 cm of water
- Deficiency of effective circulating blood volume
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- Heart failure cells are:
- Fibrocytes in myocardium
- Aschoji's giant cells
- Haemosiderin laden macrophages in alveoli
- Hypertrophic myocardial fibres
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- Synthesis of DNA occurs in Which phase of cell A cycle
- Mitosis - M phase
- Gap - G2 phase
- Gap- G1 phase
- Synthesis - S phase
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- The cells which have the capacity to multiply through out their life:
- Stable cells
- Permanent cells
- Labile cells
- None of the above
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- Which of the following has least capacity for regeneration:
- Cardiac muscle
- Skeletal muscle
- Neurons
- All of the above
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- Granulation tissue contains:
- Giant cells
- Fibroblasts
- Endothelial cells
- B&C
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- The first even in primary wound healing:
- Epithelial changes
- Organization
- Formation of blood cloth
- Acute inflammatory response
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- Wounds which are clean uninfected and surgically incised, with edge of wounds approximated by sutures heal by:
- Primary intention
- Secondary intention
- Cicatrisation
- All of the above
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- Large open wounds that are characterized by tissue loss and repaired by formation of granulation tissue in the floor of the wound is characteristic of:
- Secondary healing
- Primary healing
- Cicatrisation
- Regeneration
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- Incomplete fractures of the bone are called:
- Comminuted fracture
- Compound fracture
- Simple fracture
- Green stick fracture
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- Peripheral nerve regenerates at the rate of ___ mm per day:
- 1
- 2
- 0.5
- 5
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- All of the following promotes wound healing except:
- Protein
- Steroids
- Vitamin C
- Adequate oxygen supply
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- Correct sequence of cell cycle
- Go-G1-S-G2-M
- Go-G1-G2-S-M
- Go-M-G2-S-G1
- Go-G1-S-M-G2
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- Epitheloid cells are seen in all of the following except:
- Tuberculosis
- Granulation tissue
- Syphilis
- Sarcoidosis
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- Which of the following statement about fibrinous exudate is FALSE?
- It is associated with many types of severe inflammation
- It has low protein content
- It has fibrin precipitates
- It induces connective tissue organization
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- Some micro organisms produce a diffuse spreading inflammatory reaction due to the elaboration of:
- Coagulase
- Peroxidase
- Bradykinin
- Hyaluronidase
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- An acute inflammatory focus would attract:
- Monocytes
- Plasma cells
- Neutrophils
- Basophils
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- Granuloma is characterized by all of the following except:
- A specific type of chronic inflammation
- Accumulation of modified macrophages
- Initiated by a number of infectious and non infectious agents
- A reaction of acute inflammation
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- Which cell releases vasoactive amine so as to increase vascular permeability?
- Leukocyte
- Macrophage
- Mast cell
- Fibroblast
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- Prostaglandins are synthesized from:
- RNA template
- Rough endoplasmic reticulum
- Polyunsaturated fatty acids
- None of the above
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- Transudate is characterized by:
- Associated inflammatory conditions
- Low protein content
- Tendency to clot
- Specific gravity of above 1.018
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- Edema occurs due to:
- Increased capillary permeability
- Decreased capillary permeability
- Decreased interstitial fluid
- Decreased blood flow
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- Disappearance of nuclear chromatin is called as:
- Pyknosis
- Karyolysis
- Karyorrhexis
- None
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- A patient has increased number of columnar cells in lower esophagus. He has which of the following change:
- Dysplasia
- Anaplasia
- Metaplasia
- Normal histology
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- Saddle embolus causes sudden death by blocking:
- Coronary arteries
- Cerebral arteries
- Pulmonary arteries
- Renal arteries
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- Egg shell calcification of Hilar Lymphnode is associated with:
- Silicosis
- Asbestosis
- Byssinosis
- Anthracosis
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This download link is referred from the post: DNB 2012 June Previous Question Papers-(Diplomate of National Board) Under NBE
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