Download PTU B.Pharmacy 2020 March 3rd Sem 46123 Pharmaceutical Chemistry IV Question Paper

Roll No. ____________

Total No. of Questions : 10

Total No. of Pages : 02

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B.Pharmacy (Sem.-3)

PHARMACEUTICAL CHEMISTRY-IV (ORGANIC CHEMISTRY/ORGANIC CHEMISTRY-II)/ORGANIC CHEMISTRY

Subject Code : PHM-232

M.Code : 46123

Time : 3 Hrs.

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Max. Marks : 80

INSTRUCTIONS TO CANDIDATES :

1. SECTION-A is COMPULSORY consisting of FIFTEEN questions carrying TWO marks each.
2. SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt any FOUR questions.
3. SECTION-C contains FOUR questions carrying TEN marks each and students have to attempt any THREE questions.

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SECTION-A

1. Write short notes on :
   1. What is saponification value?
   2. Draw structures of adenine and uracil.
   3. Give the IUPAC name of pyrimidine.
   4. Difference between nucleotides and nucleosides.

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   5. What do you mean by glycolipids?
   6. What is Ruffs degradation?
   7. Maltose is a disaccharide of which two sugar components?
   8. Draw structure of theophylline.
   9. Explain Diels-Alder reaction.

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   10. Draw the structures of positively charged side chain containing amino acids.
   11. What are the factors responsible for protein denaturation?
   12. Briefly explain epimerization in monosaccharides.
   13. Comment on "tautomerism in imidazole".
   14. Comment on "Lactam-Lactim tautomerism in nitrogenous base of nucleic acid".

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   15. Why pyridine is less basic than aliphatic amine?

SECTION-B

2. Describe reactions of imidazole?
3. Explain the Killani synthesis of glucose.

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4. Describe the reactions of amino acid involving both carboxylic and amino group.
5. What are phospholipids? Describe the structure of various types of phospholipids.
6. What are Xanthine bases? Describe Traube synthesis of caffeine.

SECTION-C

7. Describe the importance synthesis and chemical reactions of pyridine.

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8. Give an account of the chemistry and structure of glucose including its cyclic structure.
9. Give the structures of nucleotides present in DNA. Describe the salient features of Watson Crick model of DNA double helix structure.
10. What are a- ß unsaturated carbonyl compounds? Compare nucleophilic and electrophilic addition reactions of these compounds.

NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.

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