Download PTU B.Pharmacy 2020 March 5th Sem 70429 Pharmacology I Question Paper

Roll No. _________________________________ Total No. of Pages : 02

Total No. of Questions: 10

B.Pharma (2012 to 2016) (Sem.-5)

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PHARMACOLOGY-I

Subject Code : BPHM-503

M.Code : 70429

Time: 3 Hrs. Max. Marks : 80

INSTRUCTION TO CANDIDATES :

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1. SECTION-A is COMPULSORY consisting of FIFTEEN questions carrying TWO marks each.
2. SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt any FOUR questions.
3. SECTION-C contains FOUR questions carrying TEN marks each and students have to attempt any THREE questions.

SECTION-A

1. Write in brief the following:
   1. Define Prodrug with the help of example.

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   2. Give two factors modifying drug absorption.
   3. Differentiate between tolerance and dependence.
   4. What is the significance of bioassay?
   5. Give two clinical uses of norepinephrine.
   6. Differentiate between synergism and antagonism.

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   7. Define Clearance and give its formula.
   8. What is the clinical use of disulfiram?
   9. Give two disadvantages of intravenous route.
   10. Why Rofecoxib was withdrawn from the market?
   11. Give two ideal properties of general anesthetics.

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   12. Name two atypical antipsychotics.
   13. Why Dopamine is given in combination with carbidopa?
   14. Define Pharmacogenetics.
   15. Give two adverse effects of tricyclic antidepressants.

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SECTION-B

2. Explain in detail the neurohumoral transmission in central nervous system.
3. Give the mechanism of action of:
   1. Lidocaine
   2. Tubocurarine

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4. Explain the following drug interactions:
   1. NSAIDs and high ceiling diuretics
   2. MAO inhibitors and tyramine
5. Describe various factors modifying drug action.
6. Discuss general management of a poisoned patient.

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SECTION-C

7. Classify antiparkinsonian drugs. Explain mechanism of action and adverse effects of each category.
8. Write a note on following:
   1. Atypical antipsychotics
   2. Newer antiepileptics

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9. Define Bioassay. Describe different types of bioassays.
10. Explain the mechanism of action, pharmacological actions, adverse effects and clinical uses of morphine.

NOTE: Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.

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