First Year MBBS Examination
I MBBS PHYSIOLOGY PAPER I
Time: 3 hours
Max Marks: 100
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Date: 20-01-2023Instructions: INSTRUCTIONS: Attempt all questions in both
sections: (Use separate answer book for each section)
Section 1
1. Fill in the blanks:
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a. Sex chromosome karyotype 47 XXY is known as__________ syndrome.
b. Cessation of menstrual cycle after the reproductive age is
called as __________.
c. Diabetic ketoacidosis is characterized by rapid deep
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respiration known as __________ breathing.d. The jumping of depolarization from node to node in
myelinated nerve is known as __________ conduction.
e. Parkinsonism is due to o deficiency of __________
neurotransmitter.
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f. The yellowish pigmented spot at the posterior pole of the eyeis called __________.
2. Answer the following MCQ:
a. Fertilization of ovum normally occurs in; a) Uterus b) Cervix
c) Fallopian tube d) None of the above
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b. Medial geniculate body is concerned with a) Hearing b)Vision c) Smell d) Taste
c. Aspirin decreases body temperature when given during
pyrexia by, a) Decreasing heat production b) Decreasing
interleukin-1 c) Decreasing prostaglandin synthesis d)
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Decrease release of pyrogend. Acromegaly a) Occurs in children b) Results in tall person c)
Causes enlargement of membranous bones d) Causes
reduction in blood glucose level
3. A 50 year old obese man comes to outpatient department with
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presenting complaints of tiredness, increased frequency ofurination, increased appetite and excessive thirst over past few
weeks. On examination his vital parameters are normal. Blood
sugar (Random) is 325 mg/dl. Based on the above case
scenario, answer the following questions:
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a. What is the most probable diagnosis?b. Explain the pathophysiology of the disease diagnosed.
c. What further investigations you would like to suggest for this
patient?
4. write short note on (Any Five).
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a. Color vision. (C2- 1114)b. Auditory pathway (C2- 1072)
c. Na+- K+ pump. (C1- 18)
d. Circadian rhythm.
e. Gate control theory of pain. (A.873) (8.807) (C2- 904)
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f. Pathophysiology of fever. (C1- 573)5. Explain briefly (Any Three).
a. Muscle spindle (C2- 881)
b. Spermatogenesis (A.476) (8.637) (C2- 790)
c. Rapid eye movement (REM) sleep.
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d. Gibbs - Donnan effect.Section 2
1. Describe origin, function and salient features of pyramidal
tracts. Discuss differences between upper and lower motor
neuron lesions.
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2. What will happen and why (Any Five).a. If growth hormone deficiency occurs in children.
b. To basal body temperature at the time of ovulation. (C2- 809)
c. To muscle tone in Parkinson's disease.
d. To vision if right optic tract gets damaged.
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e. To thermoregulatory responses if a person gets exposed tocold.
f. To cell volume if Na+ - K+ pump is inhibited.
3. Explain briefly (Any Four).
a. Parturition.
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b. Negative feedback.c. Motor aphasia. (C2- 1039)
d. Conditioned reflexes.
e. Endocrine function of testis.
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