RUHS
First Year MBBS Examination
I MBBS BIOCHEMISTRY PAPER I
Date: 01-07-2019
Time: 3 hours

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Max Marks: 50
Instructions: INSTRUCTIONS: 1. Que. No.1 and
5 in section A and B are compulsory. Attempt
ANY TWO questions from rest of the questions
in each section. 2. Use separate answer sheet

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for each section.
Section 1
1.Describe: (10)
a. Outline the main steps of tricarboxylic acid
cycle.

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b. Explain the regulation and energetic of the
tricarboxylic acid cycle.
2.Discuss (8)
a. Von Gierke's disease(A.269)
b. Beriberi (A.139)

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c. Chylomicrons
d. Essential fatty acids
3.Discuss in detail, the dictary sources,
biochemical role and deficiency disorders of
Vitamin - D. (8)

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4.Discuss (8)
a. Uncouplers of electron transport chain
b. Products of Glycine metabolism (A.344)

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Section 2
5.Describe in detail about metabolism and

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regulation of Ketone bodies. Add a note on
diabetic Ketoacidosis. (8)
6.Explain: (0)
a. Glucose transporters
b. Reactions catalyzed by PLP

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7.Discuss: (8)
a. Nitric oxide
b. Salvage pathway (A.393)
8.Write short note on: (8)
a. Fate of Pyruvate

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b. Cardiac enzymes
c. Creatinine clearance
d. HDL
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