First Year MBBS Examination
I MBBS PHYSIOLOGY PAPER II
Time: 3 hours Date: 11-04-2023 Max Marks:
100
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Instructions: INSTRUCTIONS: Attempt allquestions in both sections: (Use separate
answer book for each section)
Section 1
1. Fill in the blanks: (6)
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a. Life span of RBC is _____________ days.b. Intrinsic factor is secreted by which
_____________ cells.
c. Cholelithiasis is presence of stone in
_____________
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d. Capillaries are called as _____________vessels.
e. Erythropoietin is produced mainly by
_____________
f. Sympathetic stimulation of parotid gland
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results in _____________ secretion of saliva.2. Choose the correct option in the following
multiple choice questions: (4)
a. Normochromic macrocytic RBCs are found in
a) Megaloblastic anemia b) Iron deficiency
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anemia c) Hemorrhagic anemia d) Sickle cellanemia
b. Shift of oxygen-haemoglobin dissociation
curve to the right can occur due to a)
Decreased H ion concentration b) Increased
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CO2 concentration c) Decreased temperatured) Presence of large quantities of foetal
haemoglobin
c. The law relating to distending pressure and
tension in a blood vessel wall is, a) Frank-
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starling's law b) Marey's law c) Law ofLaplace d) Einthoven's law
d. Tendency of turbulent flow is maximum in; a)
Arterioles b) Capillaries c) Aorta d) Inferior
vena cava
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3. A 40-year old male met with an accident.He fell on the ground and got multiple injuries.
He was taken to the casualty of a nearby
hospital after 1 hour. He was bleeding
profusely from his wounds. He was drowsy.
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On examination, it was found that his radialpulse was 115/ mins and thready. His skin was
pale, extremities were cold. Arterial blood
pressure was 70/50mm of Hg. a) What is your
probable diagnosis? b) What was cause of
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rapid pulse and his cold clammy skin? c) Whatis the physiological basis of management?
(15)
4. Write short notes on (Any five) (10)
a. Lung surfactant
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b. Landsteiner law
c. Deglutition apnoea (C1-215)
d. QRS complex
e. Plasma proteins
f. Segmentation contraction
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5. Explain briefly (Any three): (15)a. Juxta glomerular apparatus
b. Regulation of hydrochloric acid (HCl)
secretion
c. Heart sounds (A.544) (B.211) (C1-282,291)
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d. Stagnant hypoxiaSection 2
1. Define cardiac output. Give its normal
value. Explain the determinants of cardiac
output. Mention the method of measuring
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cardiac output. Add a note on cardiacindex. (20)
2. What will happen & why (Any Five) (10)
a. To pH urine at high altitude.
b. To gastric emptying time fatty diet. (A.274)
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(B.475)(C1-226)c. To pulmonary blood flow distribution when
alveolar PO decreases.
d. If person has platelet count less than
50.000/uL. (C1-95)
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e. If plasma colloid osmotic pressure insystemic circulation is decreased. (C1-57)
f. Level of vitamin B and folic acid in blood in
reduced.
3. Explain briefly (Any four) (20)
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a. Mismatched transfusion.b. Transport maximum for glucose (C1-529)
c. Proton pump inhibitors.
d. Fats of haemoglobin (C2- 902)
e. Vitamin k.
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