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Third year Fifth Semester
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Question bank
Subject title- IMMUNOLOGY
Class: B.Sc Group: Common for MbBcC & MbBtC
Unit - I History of Immunology
Short answers
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- Innate Immunity
- Acquired Immunity
- Humoral Immunity
- Cell Mediated Immunity
- Antigen
- Antigenic determinants
- Haptens
- Antibodies
- Ig D
- IgE
- IgA
- Ig G
- Ig M
- Complement
- Opsonin-Dependent
- Opsonin Independent
- Epitopes
- Super antigen
- Antigenicity
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Long answers
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- What is Immunity in what respect it is differentiated from Immune response?
- Give an account of scope of Immunology?
- Give a detail account of development of immunology?
- What is innate Immunity? Give an account of types of Innate Immunity?
- What is humoral Immunity? Describe the process of humoral Immunity?
- What is cell mediate Immunity? Describe the process of cell mediate Immunity?
- Define an antigen & an Immunogen. In what respect the Immunogen differ from antigen?
- Describe different types of antigen?
- What are antibodies? Why a T-shaped antibody molecule became Y-shaped after binding to antigen?
- Describe different types of antibodies?
- What is complement system? Write different types of complement system?
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Unit II - Cells & Organs of Immune System
Short answers
- Thymus
- Bursa of fabricus
- Bone marrow
- Spleen
- Lymphnodes
- MACT
- B-lymphocytes
- T-lymphocytes
- Null cell
- Monocytes
- Macrophage
- Neutrophills
- Basophills
- Eosinophills
- Peyer’s patch
- Hematopoiesis
- MHC
- Dendritic cell
- Mast cell
- Antigen Present cell
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Long answers
- Describe briefly about primary lymphoid organs & summarize their functions in Immune response?
- Describe briefly about secondary lymphoid organs? List out secondary lymphoid organs & summarize their functions in immune response?
- What is B - lymphocytes? Give an account and their characteristics & differentiation & antibody formation?
- What do you now about T - lymphocytes? How do they originate & differentiate in the body?
- Describe briefly about Natural killer cells?
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Unit III - Antigen & Antibody Reaction
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Short answers
- Complement
- Alternative pathway
- Classical pathway
- Lectin pathway
- Agglutination
- Blood groups
- Precipitation
- Neutralization
- Complement fixation
- ELISA
- RIA
- Immunofluorescence
- Antibody affinity
- Gross reaction
- Equilibrium
- Antibody avidity
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Long answers
- Define antigen - antibody interaction? Explain briefly the various features of antigen - antibody interaction in Vivo.
- What is ELISA? Give an account on different type of ELISA?
- Briefly explain ABO AND Rh blood groups and discuss their significance?
- Explain briefly about RIA?
- Explain briefly the various features of antigen - antibody interaction in Vitro.
- What is complement system? Write different types of complement system?
- Describe the process of alternative pathway?
- Describe the process of Classical pathway?
- Describe the process of Lectin pathway?
- Describe briefly about Complement fixation?
- Describe briefly about Immunofluorescence?
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Unit IV - Immunological processes and application.
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Short answers.
- Hypersensitivity.
- Delayed hypersensitivity.
- Immediate hypersensitivity.
- Autoimmunity.
- Polyclonal antibodies
- Monoclonal antibodies
- Vaccines.
- Natural vaccine
- Recombinant vaccine.
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Long answers
- Describe briefly about-Polyclonal antibodies?
- Describe briefly about Monoclonal antibodies?
- Give an account of the technology used in the production of Monoclonal antibodies?
- Briefly discuss the various applications of Monoclonal antibodies?
- What is hypersensitivity? Write different types of hypersensitivity reaction?
- Write an essay on Autoimmunity?
- Define vaccine? Describe briefly about various types of vaccine.
- Describe briefly about recombinant vaccine.
- Describe briefly about Natural vaccine.
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