OU B.Sc Life Sciences 2021 Important Question Bank || Osmania University (Important Questions)
Subject Title: Medicinal Chemistry
Year: II
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Semester: VI
Updated on: 25-3-19
Unit - I:
- Define the following terms. a) Drug b) Pharmacology c) Pharmacophore d) Pharmacodynamics e) Pharmacokinetics f) Metabolites g) Antimetabolites
- Write a note on Therapeutic Index.
- Explain the classification of drugs with examples based on structure & therapeutic activity.
- Describe the mechanism of ADME.
- Explain routes of administration of drugs?
- What is disease? Explain different types of diseases with their preventive methods.
- Define Enzyme? Write the mechanism of enzyme action.
- Write about the factors affecting enzyme action.
- Give a note on enzyme specificity.
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Unit - II:
- Explain enzyme inhibitors and their importance.
- Discuss about the types of inhibition with examples.
- Define receptors? Explain drug-action receptor theory.
- Describe mechanism of drug-action.
- Write the concept of Agonist & Antagonist with examples.
- Explain Drug-receptor-interactions involved in drug-receptor complex.
- What is the role of -OH,NH, group in drug-receptor binding.
- What is the role of Quarternery Ammonium salts & double bond in drug-receptor binding.
- Explain structure-activity relationships of drug molecules with suitable example.
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Unit - III:
- Write Synthesis & Therapeutic activity of 1) Sulphanilamide 2) Dapsone 3) Penicillin-G
- Write Synthesis & Therapeutic activity of Chloroquine.
- Write Synthesis & Therapeutic activity of AZT.
- Write Synthesis & Therapeutic activity of Cisplatin.
- Write Synthesis & Therapeutic activity of Isoniazide.
- Explain about the antidiabetic drugs with suitable examples.
- Write a note on anti-inflammatory drug.
- Explain antipyretic drugs with example.
- Give short notes on Omeprazole.
- Define Anesthetics? Give its classification.
- Give a short notes on local anesthetics with examples.
- Give the advantages and disadvantages of Nitrous oxide and chloroform.
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Unit - IV:
- Write a short notes on a) Hormones b) Neurotransmitters
- Explain anti thyroid drug — Carbimazole.
- Explain sources & deficiency disorders and remedy of vitamins A,D,E.
- Explain sources & deficiency disorders and remedy of vitamins K,B,C.
- Explain about anti Parkinson drug-Levodopa.
- Give a note on Adrenergic drugs-Salbutamol, Atenolol.
- Explain about Fluoxetine.
- Give a note on micronutrients and it's sources, deficiency disorders.
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