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Rajiv Gandhi University of Health Sciences, Karnataka
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MBBS (Phase - II) Degree Examination - JUNE 2017
Pharmacology - Paper I (Revised Scheme)
Q.P. CODE: 1060
Max. Marks: 100 Marks
Your answers should be specific to the questions asked
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Draw neat, labeled diagrams wherever necessaryTime: Three Hours
LONG ESSAYS 2 x 9 = 18 Marks
- Classify antianginal drugs. Explain pharmacological actions, adverse effects and uses of nitrates.
- Define the term drug biotransformation. Describe the different types of biotransformation with suitable examples.
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SHORT ESSAYS 10 x 5 = 50 Marks
- Merits and demerits of oral route of drug administration
- Antiplatelet agents
- Mechanism of action, therapeutic uses and adverse effects of Digoxin.
- Pharmacotherapy of myocardial infarction
- Inhalational general anaesthetic agents
- Therapeutic uses and adverse effects of phenytoin
- Mechanism of action and therapeutic uses of succinylcholine
- Complications of diuretic therapy
- Mechanism of action and therapeutic uses of losartan
- Mechanism of action and therapeutic uses of lignocaine
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SHORT ANSWERS 16 x 2 = 32 Marks
- Polypeptide drugs are ineffective by mouth - give reason.
- Rationale of using Physostigmine in ‘Atropine poisoning.
- Disadvantages of thiopental sodium
- Rationale of using Dantrolene'in malignant hyperthermia.
- Name four nasal decongestants.
- Rationale for using morphine in acute left ventricular failure
- Two adverse effects of calcium channel blockers
- Name two beta-blockers with vasodilator property.
- Name two oral iron preparations.
- Name two drugs used in absence seizures.
- Name two Monoamine Oxidase inhibitors.
- Edrophonium is used in diagnosis of myasthenia gravis — give reason.
- Name two drugs causing Parkinsonism.
- Write any four uses of adrenaline
- N-acetylcysteine is used as antidote in paracetamol poisoning - give the rationale.
- Mention two advantages of Selective Serotonin Reuptake Inhibitors (SSRI).
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