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Rajiv Gandhi University of Health Sciences, Karnataka
MBBS (Phase - II) Degree Examination - JUNE 2016
Time: Three Hours Max. Marks: 90 Marks
Pharmacology (Old Scheme)
Q.P. CODE: 1008
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Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS 2 x 10 = 20 Marks
- Classify beta-adrenergic blocking drugs. Write therapeutic uses and adverse effects of Propranolol.
- Classify drugs for peptic ulcer. Mention mechanism of action, pharmacokinetics and therapeutic uses of proton pump inhibitors.
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SHORT ESSAYS 10 x 5 = 50 Marks
- Write advantages of benzodiazepines over barbiturates as hypnotic/sedative.
- Explain different types of drug antagonism with suitable examples.
- Explain therapeutic uses of calcium channel blockers.
- Discuss adverse drug reaction profile of oral contraceptive pills.
- Write a note on selective serotonin reuptake inhibitors (SSRI).
- Classify semisynthetic penicillins. Explain rationality of combining amoxicillin with Clavulanic
- Classify oral anticoagulants. Write their therapeutic uses.
- Discuss drug therapy for diarrhoea.
- Explain clinical uses of prostaglandin and their analogues.
- Explain general toxic effects of anticancer drugs and the measures to overcome them.
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SHORT ANSWERS 10 x 2 = 20 Marks
- Write therapeutic indications of Bromocriptine.
- Write mechanism of action and uses of atorvastatin.
- Enumerate Fibrinolytics. Explain their mechanism of action in brief.
- Enumerate AT1 receptor antagonists. Mention their advantages over Angiotensin converting enzyme inhibitors.
- What is tamoxifene citrate? Write its therapeutic indication.
- Define adverse drug reaction (ADR) and explain different types of ADR.
- Write a note on lepra reaction.
- State the pharmacological basis for use of salbutamol in therapy of bronchial asthma.
- Write two advantages and two disadvantages of intramuscular route of drug administration.
- Discuss drug therapy of status epilepticus.
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