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Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - OCT-2019
Time: Three Hours Max. Marks: 80 Marks
Biochemistry — Paper III (RS-3 Scheme)
Q.P. CODE: 3159
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Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
- Define electrophoresis. Explain the separation of serum or plasma proteins by agarose gel electrophoresis. Add a note on the reference intervals of protein fractions.
- Explain the steps ß-oxidation of palmitic acid. Discuss the energetics.
- What are tumour markers? Classify them with suitable examples. Explain the principle of any one tumour marker and give its clinical significance.
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SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
- Discuss the biochemical functions of vitamin D.
- Discuss the pre-analytical variables in a clinical laboratory giving suitable examples.
- Describe the translation process in eukaryotes.
- Name the thyroid hormones. Give the clinical significance. Add a note on their laboratory evaluation.
- Give the principle and procedure of flame photometry.
- What is a quality control material? Write the procedure for in-house preparation of quality control
- Explain isoenzymes? Give one example and mention its application in clinical diagnosis.
- Explain the transport of ABG sample. Name the equipment and important parameters analysed. Explain the precautionary measures before analyzing the sample.
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SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
- Atherosclerosis
- How are the gall stones formed? Mention the qualitative tests and their analysis.
- Clinical utility of pancreatic amylase and lipase
- Levey-Jenning’s control chart
- Hemochromatosis
- Nutritional importance of carbohydrates and lipids
- Biochemical defect in Galactosemia. Laboratory evaluation of Galactosemia.
- Troponin I and CK as cardiac markers
- Anticoagulant role of Vitamin K
- Purpose of POCT in a Hospital setting. Give one example of POCT and mention its use.
- What is BMR? Explain the factors affecting the same.
- Significance of HMP pathway
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