KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE ? 506 002
MBBS FIRST YEAR SUPPLEMENTARY EXAMINATIONS: NOVEMBER,2025
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PHYSIOLOGYPAPER ? II
Time: 3 Hours
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Max Marks: 100Note: Answer all questions
Give Diagrammatic representation wherever necessary
Multiple Choice Questions:
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10 X 1 = 101. Which of the following cells receives direct synaptic input from Golgi tendon organs,
a) Type la inhibitory interneurons
b) Dynamic gamma motor neurons
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c) Alpha motor neurons
d) Type lb inhibitory interneurons
2. Which of the following explains why individuals in severe pain have difficulty sleeping
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without sedative medication?
a) The somatosensory cortical area
b) Pain fibres entering the dorsal horn and the
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for pain perception blocks theascending pain pathways block the sleep-
sleep-generating circuits
generating circuits
c) Ascending pain pathways provide d) The neurotransmitters used in the slow pain
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excitatory input to brainstem
pathway diffuse to neighbouring cell groups
reticular formation areas that are
and generally raise the excitability of the
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involved in maintenance of thebrain
alert, waking state
3. Which of the following is a characteristics of myelinated nerve fibres.?
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a) Decreased velocity of nerveb) Saltatory conduction
impulse
c) Increased energy requirement to
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d) Increased membrane capacitancemaintain ion gradients
4. Which of the following hormones lowers plasma level of ionized calcium?
a) Calcineurin
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b) Calcitoninc) Parathyroid hormone
d) PTH related peptide
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5. True precocious puberty differs from pseudo precocious puberty in all of the followingexcept:
a) Early development of secondary b) Presence of gametogenesis
sexual characters
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c) Normal pubertal pattern ofd) More common in females
Gonadotrophin secretion from
posterior pituitary
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6. The mechanism of action of contraceptive pills is based on:a) By inhibiting ovulation
b) By increasing the motility of fallopian tube
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c) By decreasing motility of spermsd) It blocks the entry of sperm into fallopian
tube
7. Excitation contraction coupling in skeletal muscle involves all of the following events
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EXCEPTa) ATP hydrolysis
b) Binding of Ca+ to calmodulin
c) Conformational change in
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d) Depolarization of the transverse tubule (Tdihydropyridine receptor
tubule) membrane
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8. Olfactory receptor cells belong to which group of cells?
a) Bipolar neurons
b) Fibroblasts
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c) Modified epithelial cells
d) Pseudo unipolar neurons
9. Which of the following is NOT a characteristics of an action potential
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a) Refractory period
b) Conductivity
c) Accommodation
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d) Graded response to increasing strength ofstimuli
10. In excitable cells, repolarization phase is caused due to
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a) Na+ effluxb) Na+ influx
c) K+ efflux
d) K+ influx
Essay/ Long Answer Questions:
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2 X 15 = 30
11. An young male met with accident. He is brought to the hospital. On examination he is conscious
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and coherent. He is unable to move his right upper limb and lower limb. Pain touch sensations werenot elicited. The doctor give a provisional diagnosis of spinal injury.
a) Describe Spinal injury and add a note on types of spinal injury.
b) Describe ascending and descending tracts and enumerate the sensations they carry.
c) Discuss in detail about Brown Sequard Syndrome.
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d) List the differences in UMNL and LMNL. (3+6+4+2)12. A 55 years old male comes to a physician with complaints of fatigue, increase in frequency of
voiding urine, taking excess food frequently since last 6 months. On examination of blood sample.
FBS- 140 mg/dl, PPBS- 285 mg/dl, HbA1c levels ? 8%
a) Identify the condition in the discussed case.
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b) Write in detail about the structure and bio synthesis of the hormone involved.c) Add a note on mechanism of action of hormone and enumerate the actions of hormone.
d) Add a note on the Characteristic features of NIDDM. (2+5+6+2)
Short Answer Questions:
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7 X 6 = 42
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13. Discuss the regulation of Body temperature.14. Write the properties of Synapses. Add a note on Indirect Inhibition.
15. List the types of Aphasia.
16. List the Placental Hormones and briefly explain their functions.
17. Discuss Refractory errors in detail.
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18. Describe the functions of Testosterone.19. Mechanism of smooth muscle contraction.
Very Short Answer Questions:
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6 X 3 = 18
20. Demonstrate the roles of an Indian medical graduate and relate it to the societal impact.
21. Enumerate the functions of Thalamus.
22. Physiology of aging
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23. Nerve growth factors24. Discuss about Audiometry.
25. Describe about Addison's disease. List the manifestations of it.
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