KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE ? 506 002
MBBS SECOND YEAR DEGREE EXAMINATIONS: AUGUST, 2025
--- Content provided by FirstRanker.com ---
PHARMACOLOGYPaper ?I
Time: 3 Hours
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
Max Marks: 100Note: Answer all questions
Give Diagrammatic representation wherever necessary
Multiple Choice Questions: 10 X 1 = 10
--- Content provided by FirstRanker.com ---
1. Drug administered through the following route is most likely to besubjected to first-pass metabolism:
a) Oral
--- Content provided by FirstRanker.com ---
b) Sublingualc) Subcutaneous
d) Rectal
--- Content provided by FirstRanker.com ---
2. Orphan drugs are
a) drugs with high
--- Content provided by FirstRanker.com ---
b) drugs for rare diseasetherapeutic failure
c) drugs having low
--- Content provided by FirstRanker.com ---
d) drugs with high toxicitytherapeutic margin
3. Low doses of aspirin prolong bleeding time by selectively inhibiting
--- Content provided by FirstRanker.com ---
synthesis of the following mediator in the platelets:a) Thromboxane A2
b) 5-Hydroxytryptamine
--- Content provided by FirstRanker.com ---
c) Platelet activating factor
d) Prostacyclin
4. The most effective drug in parkinsonism is:
--- Content provided by FirstRanker.com ---
a) Bromocriptine
b) Selegiline
--- Content provided by FirstRanker.com ---
c) Levodopa
d) Biperiden
5. The following analgesic lacks anti-inflammatory action:
--- Content provided by FirstRanker.com ---
a) Paracetamol
b) Ibuprofen
--- Content provided by FirstRanker.com ---
c) Diclofenac sodium
d) Piroxicam
6. The drug which undergoes 'Hofmann' elimination is:
--- Content provided by FirstRanker.com ---
a) Succinylcholine
b) Pancuronium
--- Content provided by FirstRanker.com ---
c) Vecuronium
d) Atracurium
7. fomepizole is used in which poisoning
--- Content provided by FirstRanker.com ---
a) methyl alcohol poisoning
b) morphine poisoning
--- Content provided by FirstRanker.com ---
c) strychnine poisoning
d) atropine poisoning
8. Atropine poisoning causes all except
--- Content provided by FirstRanker.com ---
a) Dilated pupil
b) Excessive salivation
--- Content provided by FirstRanker.com ---
c) Excitement
d) hot skin
9. Antidote for paracetamol poisoning is
--- Content provided by FirstRanker.com ---
a) Naloxone
b) Methylene blue
--- Content provided by FirstRanker.com ---
c) N-acetylcysteine
d) Flumazenil
10. The drug of choice for status epilepticus is
--- Content provided by FirstRanker.com ---
a) Lorazepam
b) Propofol
--- Content provided by FirstRanker.com ---
c) Thiopentone
d) Sodium valproate
--- Content provided by FirstRanker.com ---
Essay/ Long Answer Questions:
--- Content provided by FirstRanker.com ---
2 X 15 = 30
11. a) Enlist the different types of receptors with examples of drugs acting through
them.
(6+2)
--- Content provided by FirstRanker.com ---
b) Describe the factors modifying drug action and their clinical significance.(5+2)
12. Classify Antidepressants. Describe the mechanism of action, therapeutic uses and
adverse effects of Tricyclic Antidepressants.
(6+3+3+3)
--- Content provided by FirstRanker.com ---
Short Answer Questions:7 X 6 = 42
13. Describe the advantages and disadvantages of Intravenous route of Drug
--- Content provided by FirstRanker.com ---
administration.14. Compare and contrast Succinylcholine and D-Tubocurarine.
15. Describe therapeutics uses and adverse effects of Alpha Blockers.
16. Classify Anticholinesterases and mention their therapeutic uses.
17. Explain the mechanisms of action, therapeutic uses and adverse effects of proton
--- Content provided by FirstRanker.com ---
Pump Inhibitors.18. Describe disease modifying Anti Rheumatoid Drugs.
19. Describe how to counsel HIV/ AIDS patient to adhere to Anti-Retroviral
Therapy.
Very Short Answer Questions:
--- Content provided by FirstRanker.com ---
6 X 3 = 18
20. Define Prodrug with two examples.
21. Enlist any two uses of Adrenaline with its rationale.
--- Content provided by FirstRanker.com ---
22. Mention the drugs used in the management of Organo Phosphorous Poisoningwith its rationale.
23. Mention three different groups of drugs used in Bronchial Asthma with one
example for each.
24. What is Malignant Hyperthermia? Mention the drug used for its treatment.
--- Content provided by FirstRanker.com ---
25. Define Tachyphylaxis. Give two examples of drugs causing Tachyphylaxis.* * * * *