KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE ? 506 002
MBBS SECOND YEAR DEGREE SUPPLEMENTARY EXAMINATIONS: JUNE,2025
PATHOLOGY
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Paper -ITime: 3 Hours
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Max Marks: 100
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Note: Answer all questionsGive Diagrammatic representation wherever necessary
Multiple Choice Questions: 10 X 1 = 10
1 Epstein Barr virus causes all EXCEPT:
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a) Infectious Mononucleosisb) Nasopharyngeal carcinoma
c) Burkitt's lymphoma
d) Acute myeloid leukaemia
2 Interstitial pulmonary fibrosis can occur due to all except:
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a) Busulfan
b) Nitrofurantoin
c) Tetracycline
d) Bleomycin
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3 All of the following is true for anaemia of chronic diseases except?a) Low serum iron levels
b) Low erythropoietin
c) Increased hepcidin
d) Low ferritin
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4 Defect in sickle cell disease isa) Glutamate residue instead of a
b) Valine residue instead of a
valine residue at the 6th amino
glutamate residue at the 6th
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acid position in (3-globin
amino acid position in 13-globin
c) Glutamate residue instead of a
d) Valine residue instead of a
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valine residue at the 6th aminoglutamate residue at the 6th
acid position in a -globin
amino acid position in a-globin
5 Hodgkin lymphoma with frequent mononuclear cells and classical Reed
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Sternberga) Nodular sclerosis
b) Lymphocyte depletion
c) Mixed cellularity
d) Lymphocyte predominance
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6 Idiopathic thrombocytopenic purpura is characterized by:a) Decreased platelet survival
b) Decreased production of
platelets
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c) Hypersplenismd) Dilutional thrombocytopenia
7 Bombay phenotype are the individuals who:
a) Lack H genes and therefore H
b) Possess A, B antigens
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substance
c) Secrete excessive amount of H
d) Lack C, D and E antigens
substance
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8 Cyclin dependent Kinases are all excepta) P57
b) P21
c) P53
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d) P279 Not a stain for Amyloid is
a) Congo red
b) Methyl violet
c) Triphenyl tetrazolium chloride
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d) Thioflavin T10 Not a cause of oedema is
a) Increased hydrostatic pressure
b) Increased plasma oncotic
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pressurec) Lymphatic obstruction
d) Sodium retention
Essay/ Long Answer Questions:
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2 X 15 = 30
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11. Define Apoptosis. Describe morphological features and mechanism of Apoptosis.(2+6+7)
12. Define and Classify of Leukaemia. Discuss the Chromosomal abnormality and lab
findings in Chronic Myeloid Leukaemia.
(2+3+4+6)
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Short Answer Questions:7 X 6 = 42
13. Discuss about pathological Calcification.
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14. Describe Gaucher's Disease.15. Von Willebrand's Disease.
16. Transplant rejection.
17. Factors affecting Wound Healing.
18. Pathology of Vitamin D deficiency.
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19. Aplastic Anaemia.Very Short Answer Questions:
6 X 3 = 18
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20. Three types of Necrosis with examples.
21. CSF findings in Pyogenic Meningitis.
22. Three Opportunistic infections in HIV infection.
23. Morphology of Megaloblast.
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24. Enumerate anticoagulants in Haematology.25. Indications of Semen Analysis.
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