PAPER CODE: MB2019113
KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA? 506 002
MBBS SECOND YEAR DEGREE SUPPLEMENTARY EXAMINATIONS: JANUARY,2026
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PATHOLOGYPAPER -I
Time: 3 Hours
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Max Marks: 100Note: Answer all questions
Give Diagrammatic representation wherever necessary
Multiple Choice Questions: 10 X 1 = 10
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1. Lymphocytosis is not associated with:a) Infectious mononucleosis b) Mumps
c) German measles
d) Parasitic infestations
2. Microcytic blood picture is seen in all except
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a) Thalassemiab) Sideroblastic anaemia
c) Pernicious anaemia
d) Anaemia of chronic disorders
3. Total iron binding capacity is raised in
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a) Iron deficiency anaemiab) Renal disease
c) Malignant disease
d) Infections
4. Defective platelet aggregation is seen in
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a) Bernard-Soulierb) Glanzman's syndrome
syndrome
c) Haemophilia
d) Vitamin K deficiency
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5. An young man met with a road accident and had left femoral fractureafter which his leg was immobilized in a plaster cast for 6 weeks
following which the diameter of the left calf was decreased in size.
This change in size is most likely to result from which of the
following alterations in his calf muscles?
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a) Hyperplasiab) Atrophy
c) Dystrophy
d) Hyalinosis
6. In case of tissue subjected to hypoxic damage the cells in this tissue
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begin to swell with chromatin clumping in cell nuclei, ATPases areactivated, and ATP production decreases. Which of the following ions
accumulating in mitochondria and the cytosol contributes most to
these findings and to eventual cell death?
a) Ca2+
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b) Cl-c) HCO3-
d) K+
7. A child with a history of recurrent infections with pyogenic bacteria
had an area of soft tissue necrosis and the microscopic examination of
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the biopsy obtained from this tissue showed microbial organisms, butvery few neutrophils. The analysis of the case showed neutrophil
functional defect involving rolling. The most probable cause of
increased susceptibility to infection is a defect involving which of the
following molecules?
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a) Selectinsb) Complement C3b
c) Integrins
d) Leukotriene B4
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8. Diabetic foot is an example of:
a) Dry gangrene
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b) Wet gangrenec) Gas gangrene
d) Necrotizing inflammation
9. Enzyme which prevents cell ageing
a) Catalase
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b) Superoxide dismutasec) Metalloproteinase
d) Telomerase
10. Amyloidosis results from abnormal folding of proteins, which are
insoluble, aggregate, and deposit as:
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a) Fibrils in extracellularb) Intracellular deposits
tissues
c) Intranuclear inclusions
d) In the meninges
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Essay/ Long Answer Questions:--- Content provided by FirstRanker.com ---
2 X 15 = 3011. Define Necrosis. Discuss in detail about different types of Necrosis with suitable
examples.
(3+12)
12. A 2-year-old child was brought Paediatric outpatient with history of failure to
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thrive. O/E child is Anaemic with mongoloid face, i.e. with Malar Eminence,Frontal bossing, X-ray skull shows hair on end appearance, moderate
splenomegaly and hepatomegaly. What is your provisional diagnosis? Discuss
about pathogenesis and lab diagnosis of this condition.
(2+7+6)
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Short Answer Questions:7 X 6 = 42
13. Fat Embolism.
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14. Special stains used to demonstrate Amyloid.15. Classify Hodgkin's disease. Add a note on Nodular Sclerosis.
16. WHO classification of AML.
17. Down's syndrome.
18. Ochronosis.
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19. Complications of Wound Healing.Very Short Answer Questions:
6 X 3 = 18
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20. Differences between Transudate and Exudate.21. Bence Jones Protein.
22. CSF in Pyogenic Meningitis.
23. Microscopy of Rhinosporidiosis.
24. Granuloma.
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25. Bone marrow picture in B12 deficiency.*****