PAPER CODE: MB2019115
KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA? 506 002
MBBS SECOND YEAR DEGREE EXAMINATIONS: JUNE, 2025
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MICROBIOLOGYPaper ?I
Time: 3 Hours
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Max Marks: 100Note: Answer all questions
Give Diagrammatic representation wherever necessary
Multiple Choice Questions: 10 X 1 = 10
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1 Robertson's cooked meat medium is an example of:a) Enriched medium
b) Enrichment medium
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c) Anaerobic medium
d) Selective medium
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2 Mechanism of direct transfer of free DNA is:a) Transformation
b) Transposition
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c) Conjugation
d) Transduction
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3 Filariasis in India is transmitted bya) Musca domestica
b) Anopheles gambiae
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c) Culex quinquefasciatus
d) Aedes aegypti
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4 BCG vaccine is an example of:a) Natural active immunity
b) Natural passive immunity
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c) Artificial passive immunity d) Artificial active immunity
5 Which of the following samples is not useful in diagnosis of Enteric
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fever?
a) Blood
b) Stool
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c) Urine
d) Sputum
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6 Which of the following parasite causes megaloblastic anaemia?a) Ancylostoma duodenale
b) Plasmodium falciparum
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c) Diphyllobothrium latum
d) All of the above
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7 Which one of the following is an enriched medium?a) Selenite F Broth
b) Peptone water
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c) MacConkey agar
d) Blood agar
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8 Organisms producing extended spectrum -lactamases (ESBL) are:a) Resistant to all penicillins-
b) Resistant to penicillins
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1st, 2nd & 3rd generationcephalosporins and
monobactams
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c) Resistant to cephalosporinsd) Resistant to cephalosporins of
of 1st,2nd & 3rd generation
4th generation
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9 Which of the following can be converted to toxoid by formaldehydea) Exotoxin
b) Endotoxin
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c) Endospore
d) All of the above
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10 All waste sharps should be discarded in:a) Cardboard boxes with blue
b) Puncture proof and leak proof
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coloured markings
white containers
c) Red coloured non-
d) Yellow coloured
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chlorinated container
container
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Essay/ Long Answer Questions:
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2 X 15 = 30
11. Define and classify Hypersensitivity Reactions. Write in detail about type IV
Hypersensitivity Reactions.
(4+4+7)
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12. A 7 year old female child presented to cardiology OPD with swollen red tenderjoints which migrated from one joint to another over a period of hours. The
child was having abnormal gait. She also complained of painless small mobile
lumps beneath the skin overlying bony prominences. On auscultation murmur
was heard over the Mitral valve area. ECG showed prolongation of P-R interval.
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Child gives a history of sore throat 3 weeks back.a. What is the probable clinical diagnosis and its aetiological agent?
b. Describe the diagnosis criteria used for this condition.
c. How will you prevent recurrence of such episodes?
(3+7+5)
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Short Answer Questions:7 X 6 = 42
13. Anaerobic culture methods.
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14. Bacterial Flagella.15. Polymerase chain reaction.
16. Transduction.
17. Methods of detecting Viral Growth in Cells.
18. Stool concentration techniques.
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19. Laboratory diagnosis of Fungal Infection.Very Short Answer Questions:
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6 X 3 = 1820. Negribody
21. Four differences between Classical and El tor Vibrios.
22. Sheathed Microfilaria.
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23. Visceral Larva Migrans.24. Give three examples of Heterophile Agglutination reactions.
25. What is the principle of a Fluorescence Microscope.
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