KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE ? 506 002
MBBS SECOND YEAR DEGREE EXAMINATIONS: AUGUST,2025
MICROBIOLOGY
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PAPER ?IITime: 3 Hours
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Max Marks: 100Note: Answer all questions
Give Diagrammatic representation wherever necessary
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Multiple Choice Questions: 10 X 1 = 101. Which of the following is not considered a potential agent of
bioterrorism and biologic warfare?
a) Yersinia pestis
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b) Botulinum toxinc) Streptococcus pyogenes d) Bacillus anthracis
2. In a patient with bubonic form of plague, all the following specimens
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are acceptable for diagnosis except
a) Stool culture
b) Blood culture
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c) Culture of lymph node
d) Acute and convalescent
aspirate
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serum3. Staphylococcus epidermidis may cause:
a) Toxic shock syndrome
b) Stitch abscess
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c) Staphylococcal scalded
d) All of the above
skin syndrome
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4. Soft chancre is caused bya) Treponema pallidum
b) Neisseria gonorrhoeae
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c) Haemophilus ducreyid) Chlamydia trachomatis
5. Tissue should be segregated in which colour bag?
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a) Yellowb) Blue
c)
Red
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d) Black
6. Subacute sclerosing panencephalitis is a complication of
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a) Mumpsb) Meas
les
c) Ru
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bellad) Rabies
7. Which of the following is not used as an indicator organism of
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faecal contamination of watera) Escherichia coli
b) Salmonella typhi
c) Faecal Streptococci
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d) Pseudomonas8. Intracellular survival of Mycobacterium tubercle bacilli inside the
macrophage is due to
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a) Inhibition of entry intob) Inhibition of entry into
host cell
phagosome
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c) Inhibition of phagosome d) Inhibition of degradationand lysosome fusion
by lysosomal enzymes
9. Cutaneous leishmaniasis is also called as
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a) Delhi boilb) Aleppo boil
c) Baghdad button
d) All of the above
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10. Gene targets for confirmation of COV1D 19 includes
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a) Spike Protein
b) Envelope protein
c) Membrane protein
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d) RNA dependent RNApolymerase
Essay/ Long Answer Questions:
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2 X 15 = 30
11. A 55-year-old male came to OPD with complaints of fever, vomiting, severe
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headache and photophobia since 2 days. On examination he had a temperature of39o C pulse rate of 96 bpm. He has recently had ear infection. Neck stiffness was
noted. Relevant sample was spent for confirmation of the diagnosis.
a. Elaborate on the sample collection.
b. Gram stain report of the sample revealed lens shaped gram-positive
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Diplococci with a halo around and plenty of the Polymorphonuclear cells.Identify the probable pathogen.
c. Elaborate on laboratory tests done to confirm the pathogen.
d. Add a note on Prophylaxis and treatment available for this pathogen.
(3+2+5+5)
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12. A farmer presented to the OPD with history of Papulo Vesicular Lesion over theneck. Which later on developed into a coal black, necrotic wound for the past 3
days, tissue from the necrotic area on Gram staining revealed Gram positive
bacilli arranged in chains.
a. What is the clinical diagnosis and causative agent?
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b. Describe the pathogenesis and various forms of clinical presentation ofthis infection.
c. Describe the laboratory investigations to confirm the diagnosis.
(2+6+7)
Short Answer Questions:
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7 X 6 = 42
13. Guinea worm infection.
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14. Gonorrhoea- pathogenesis and Lab diagnosis15. Laboratory diagnosis of Diphtheria.
16. Mumps.
17. Extra intestinal amoebiasis.
18. Mucormycosis.
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19. Lab diagnosis of Extra Pulmonary Tuberculosis.Very Short Answer Questions:
6 X 3 = 18
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20. Name three Zoonotic Diseases.21. What is the color coding for Biomedical Waste according to BMW management
rules 2016.
22. Congenital Syphilis.
23. DPT Vaccine.
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24. Name three Microfilaria of medical importance.25. Name three agents causing Ocular Mycoses.
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