Download KNRUHS MBBS 1st Year MB2019102 Biochemistry Paper II _ SEP 2025 Question Paper

PAPER CODE: MB2019102
KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE ? 506 002
MBBS FIRST YEAR EXAMINATIONS: SEPTEMBER 2025

--- Content provided by​ FirstRanker.com ---

BIOCHEMISTRY
PAPER ? II
Time: 3 Hours

--- Content provided by⁠ FirstRanker.com ---

--- Content provided by⁠ FirstRanker.com ---

Max Marks: 100
Note: Answer all questions
Give Diagrammatic representation wherever necessary

--- Content provided by​ FirstRanker.com ---

Multiple Choice Questions:

--- Content provided by FirstRanker.com ---

10 X 1 = 10
1. Pulses are deficient in

a) Lysine
b) Threonine

--- Content provided by⁠ FirstRanker.com ---

c) Methionine
d) Tryptophan

2. Which one of the following theories effectively explains the feature

--- Content provided by‍ FirstRanker.com ---

of immune response?
a) Selection theory
b) Germ line theory

--- Content provided by⁠ FirstRanker.com ---

c) Template theory
d) Clonal selection theory

3. Chronic obstructive airway disease results in

--- Content provided by​ FirstRanker.com ---

a) Respiratory acidosis
b) Metabolic acidosis

c) Respiratory alkalosis
d) Metabolic alkalosis

--- Content provided by‍ FirstRanker.com ---

4. A hormone secreted from anterior pituitary is

a) Growth hormone
b) Vasopressin

--- Content provided by‍ FirstRanker.com ---

c) Oxytocin
d) Epinephrine

5. Molecules involved in immune response are

--- Content provided by⁠ FirstRanker.com ---

a) MHC molecules
b) Cytokines

c) Chemokines
d) All the above

--- Content provided by FirstRanker.com ---

6. Antioxidant enzymes are

a) Superoxide dismutase
b) Catalase

--- Content provided by FirstRanker.com ---

(SOD)
c) Glutathione peroxidase
d) All the above

--- Content provided by⁠ FirstRanker.com ---

7. Biotransformation takes place in

a) Intestines
b) Lungs

--- Content provided by​ FirstRanker.com ---

c) Skin
d) Liver

8. Serum acid phosphatase level increases in

--- Content provided by FirstRanker.com ---

a) Carcinoma of Prostate
b) Carcinoma of Lung

c) Carcinoma of Liver
d) Carcinoma of Oesophagus

--- Content provided by FirstRanker.com ---

---

9. The predominant buffer system of plasma is the

--- Content provided by FirstRanker.com ---

a) Albumin buffer
b) Bicarbonate buffer

c) Haemoglobin buffer

--- Content provided by FirstRanker.com ---

d) Phosphate buffer

10. The Peptide that protects RBC membrane is

a) Oxytocin

--- Content provided by FirstRanker.com ---

b) Glutathione

c) Vasopressin
d) Angiotensin

--- Content provided by‌ FirstRanker.com ---

Write an essay on the following:



2 X 15 = 30

--- Content provided by FirstRanker.com ---

11. Discuss the metabolism of Glycine. Give an account on biological important
compounds synthesised from Glycine. Add a note on primary Hyperoxaluria.

(8+4+3)

--- Content provided by‌ FirstRanker.com ---

12. A 45-year-old obese lady presented to the causality with complaints of acute
right upper abdominal pain, mild fever, loss of appetite and generalized
itching. On further questioning, she gave history of frothy, clay coloured stool
and high coloured urine.
a) What is the probable diagnosis?

--- Content provided by⁠ FirstRanker.com ---

b) Mention the laboratory tests you advise to confirm the diagnosis?
c) Describe the normal bilirubin metabolism.
d) How do you relate the high coloured urine, itching and clay-coloured
stools with altered metabolic pathway of bilirubin in this condition.
(1+2+6+6)

--- Content provided by⁠ FirstRanker.com ---

Write a short essay on the following:



7 X 6 = 42

--- Content provided by⁠ FirstRanker.com ---

13. Describe the Oncogenes and their role in Cancer with examples.
14. Discuss the Renal mechanisms involved in regulation of blood pH.
15. Recombinant DNA technology and its applications.
16. What are your perspectives on lifelong learning by Physician?
17. Discuss the structure of normal Haemoglobin. Add a note on haemoglobin

--- Content provided by‌ FirstRanker.com ---

derivatives.
18. What is Transamination and its significance? List two Transaminases.
19. Structure and functions of t-RNA.
Write briefly on the following:

--- Content provided by​ FirstRanker.com ---

6 X 3 = 18
20. DNA polymerase.
21. Alkaptonuria.

--- Content provided by FirstRanker.com ---

22. What is the normal anion gap? State its importance.
23. Phase II detoxification.
24. Point mutation.
25. Porphyria Cutanea tarda.
*****

--- Content provided by FirstRanker.com ---

---