2019 Scheme
Q.P. Code: 213001
Reg. no.: .....................
Second Professional MBBS Degree Supplementary (SAY) Examinations
March 2025
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space
Draw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(1x20=20)
The MCQ questions (Q.No. i to Q.No. xx) shall be written in the space provided for answering MCQ
Responses for MCQs marked in any other part/page of the answer book will not be valued
Question Numbers i ? v are Single Response Type
i. One of the following cytokine is a powerful chemo attractant
a) Interleukin -8
c) Interleukin -6
d) Interleukin -4
ii. In Bernard-Soulier Syndrome there is defect of platelet
a) Adhesion
c) Secretion
d) Activation
iii. Leukocyte alkaline phosphatase is markedly reduced in:
a) Acute Lymphoblastic Leukaemia
c) Chronic Myeloid Leukaemia
d) Chronic Lymphocytic Leukaemia
iv. The most common cause for male hypogonadism is
a) Klinefelter's syndrome
c) Down's syndrome
d) Edward's syndrome
v. Erythrophagocytosis is a feature of:
a) Shigella infection
c) Amoeblasis
d) Cholera
Question numbers vi - x are multiple response type questions. Read the statements & mark the
answers appropriately.
1) Bronchiectasis
2) Tuberculosis
3) Sarcoidosis
4) Xanthomas
b) 2, 3 and 4 are correct
c) 1, 3 and 4 are correct
d) 1, 2 and 4 are correct
vii. Prolonged Bleeding time is seen in
2) Von Willebrand's disease
3) Haemophilia A
4) Aspirin therapy
a) 1,2 and 3 are correct
c) 1, 3 and 4 are correct
d) 1, 2 and 4 are correct
viii. Nitric Oxide is synthesized by
1) Neurons
3) Hepatocytes
4) Monocytes.
a) 1, 2 and 3 are correct
b) 2, 3 and 4 are correct
d) 1, 2 and 4 are correct
ix. Peripheral appetite suppressing signals includes
1) Leptin
2) Adiponectin
4) Ghrelin
a) 1, 2 and 3 are correct
b) 2, 3 and 4 are correct
c) 1, 3 and 4 are correct
x. Identification of plasmodium falciparum in the peripheral smear include
1) Schizont forms
2) Small thin ring forms of the parasite inside the RBC
3) Banana shaped gametocytes
a) 1, 2 and 3 are correct
b) 2, 3 and 4 are correct
c) 1, 3 and 4 are correct
d) 1, 2 and 4 are correct
questions by selecting the appropriate options given below.
xi. (A): Nucleic Acid Testing (NAT) is a better screening method in blood banking
(R): Low antibody levels are detected by NAT
a) Both A & R are correct and R is the reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
xii. (A): Hepatocytes are labile cells
(R): Hepatocytes can re enter the cell cycle and regenerate themselves
b) Both A & R are correct but R is not reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
(PTO)
xiii. (A): Metastatic Calcification is seen in Hyperparathyroidism
(R): Serum calcium levels are normal in dystrophic calcification.
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
d) A is incorrect R is correct
xiv. (A): Gandy Gamna Bodies are seen in chronic venous congestion of Spleen
(R): Chronic venous congestion of spleen causes right sided heart failure.
a) Both A & R are correct and R is the reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
xv. (A): von Willebrand factor is synthesized by Hepatocytes
(R): von Willebrand factor is a carrier protein for factor VIII
b) Both A & R are correct but R is not reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
Question Numbers xvi? xx are based on case scenarios. Read the statements and mark the answers
A 26 year old women with third degree burns developed septic shock. With 24hours she was bleeding from all
needle puncture sites, with extensive ecchymoses and petechiae and GI Bleeding. Lab studies showed Hb-
6gm/dl., platelet count 64000/cu mm., PT 20 seconds, PTT 50 seconds and D-dimer Positive.
xvi. What is your most probable clinical diagnosis
b) Immune thrombocytopenia
c) Disseminated Intravascular coagulation
d) Anaphylactic shock
xvii. Which one of the following investigation is diagnostic
b) Prothrombin time c) Thrombin Time
d) D ? dimer test
xviii. The drop in the amount of Hemoglobin is mostly due to
a) Ineffective erythropiesis
c) Aplasia of the marrow
d) Nutritional deficiency
xix. The most common morphology of red blood cells seen in the peripheral smear of the above case is
a) Microcytes
c) Drepanocytes
d) Codocytes
xx. Fibrin degradation products have
a) Potent anticoagulant effect
c) Prothrombotic effect
d) Endothelial activation effect
Long Essays.
(2x10=20)
2. A 50 year old person was admitted to the hospital with complaints of intermittent fever for the past two
Pulse rate ? 102/mt, dyspnoea present, drowsy, urine output less than 100ml/ 24 hours. Blood sample
sent for culture and sensitivity. CBC ? Hemoglobin 8g/dl, total WBC count -18000/cmm.
a) What is your provisional diagnosis
b) Describe briefly the etiopathogenesis of this condition
d) Enlist the stages of this condition
(2+3+3+2)
3. Define Leukaemia. Classify Acute Myeloblastic Leukaemia as per WHO classification. Describe the
peripheral smear and bone marrow findings with illustrations in a case of Acute Myeloid Leukaemia.
Short Essays.
(6X6=36)
4. Type II hypersensitivity reaction
5. Role of Chemical Carcinogens
7. Granulomatous inflammation
8. Opportunistic Infections
9. Factors Influencing Wound Healing
Short Answers.
10. Enlist two common indications and two absolute contraindications for bone marrow aspiration study
11. Enumerate four common laboratory tests done to confirm Multiple Myeloma
12. Enlist Four common types of Necrosis with suitable clinical examples
13. Name the four cardinal principles of Biomedical Ethics
15. Mention four common stains used to demonstrate Amyloid in the tissues
**************************
Q.P. Code: 213001
Reg. no.: .....................
Second Professional MBBS Degree Supplementary (SAY) Examinations
March 2025
--- Content provided by FirstRanker.com ---
Pathology - Paper ITime: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space
--- Content provided by FirstRanker.com ---
Answer all parts of a single question together ? Leave sufficient space between answersDraw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(1x20=20)
The MCQ questions (Q.No. i to Q.No. xx) shall be written in the space provided for answering MCQ
--- Content provided by FirstRanker.com ---
questions at page No. 51 of the answer book (the inner portion of the back cover page (PART III)).Responses for MCQs marked in any other part/page of the answer book will not be valued
Question Numbers i ? v are Single Response Type
i. One of the following cytokine is a powerful chemo attractant
a) Interleukin -8
--- Content provided by FirstRanker.com ---
b) Interleukin -2c) Interleukin -6
d) Interleukin -4
ii. In Bernard-Soulier Syndrome there is defect of platelet
a) Adhesion
--- Content provided by FirstRanker.com ---
b) Aggregationc) Secretion
d) Activation
iii. Leukocyte alkaline phosphatase is markedly reduced in:
a) Acute Lymphoblastic Leukaemia
--- Content provided by FirstRanker.com ---
b) Acute Myeloblastic Leukaemiac) Chronic Myeloid Leukaemia
d) Chronic Lymphocytic Leukaemia
iv. The most common cause for male hypogonadism is
a) Klinefelter's syndrome
--- Content provided by FirstRanker.com ---
b) Turner's syndromec) Down's syndrome
d) Edward's syndrome
v. Erythrophagocytosis is a feature of:
a) Shigella infection
--- Content provided by FirstRanker.com ---
b) Salmonellosisc) Amoeblasis
d) Cholera
Question numbers vi - x are multiple response type questions. Read the statements & mark the
answers appropriately.
--- Content provided by FirstRanker.com ---
vi. Multinucleate giant cells are seen in1) Bronchiectasis
2) Tuberculosis
3) Sarcoidosis
4) Xanthomas
--- Content provided by FirstRanker.com ---
a) 1, 2 and 3 are correctb) 2, 3 and 4 are correct
c) 1, 3 and 4 are correct
d) 1, 2 and 4 are correct
vii. Prolonged Bleeding time is seen in
--- Content provided by FirstRanker.com ---
1) Thrombocytopenia2) Von Willebrand's disease
3) Haemophilia A
4) Aspirin therapy
a) 1,2 and 3 are correct
--- Content provided by FirstRanker.com ---
b) 2, 3 and 4 are correctc) 1, 3 and 4 are correct
d) 1, 2 and 4 are correct
viii. Nitric Oxide is synthesized by
1) Neurons
--- Content provided by FirstRanker.com ---
2) Endothelial cells3) Hepatocytes
4) Monocytes.
a) 1, 2 and 3 are correct
b) 2, 3 and 4 are correct
--- Content provided by FirstRanker.com ---
c) 1, 3 and 4 are correctd) 1, 2 and 4 are correct
ix. Peripheral appetite suppressing signals includes
1) Leptin
2) Adiponectin
--- Content provided by FirstRanker.com ---
3) Obestatin4) Ghrelin
a) 1, 2 and 3 are correct
b) 2, 3 and 4 are correct
c) 1, 3 and 4 are correct
--- Content provided by FirstRanker.com ---
d) 1, 2 and 4 are correctx. Identification of plasmodium falciparum in the peripheral smear include
1) Schizont forms
2) Small thin ring forms of the parasite inside the RBC
3) Banana shaped gametocytes
--- Content provided by FirstRanker.com ---
4) Multiple ring forms in a single RBCa) 1, 2 and 3 are correct
b) 2, 3 and 4 are correct
c) 1, 3 and 4 are correct
d) 1, 2 and 4 are correct
--- Content provided by FirstRanker.com ---
Question numbers xi ? xv consists of two Statements-Assertion (A) and Reason (R). Answer thesequestions by selecting the appropriate options given below.
xi. (A): Nucleic Acid Testing (NAT) is a better screening method in blood banking
(R): Low antibody levels are detected by NAT
a) Both A & R are correct and R is the reason for A
--- Content provided by FirstRanker.com ---
b) Both A & R are correct but R is not reason for Ac) A is correct R is incorrect
d) A is incorrect R is correct
xii. (A): Hepatocytes are labile cells
(R): Hepatocytes can re enter the cell cycle and regenerate themselves
--- Content provided by FirstRanker.com ---
a) Both A & R are correct and R is the reason for Ab) Both A & R are correct but R is not reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
(PTO)
--- Content provided by FirstRanker.com ---
xiii. (A): Metastatic Calcification is seen in Hyperparathyroidism
(R): Serum calcium levels are normal in dystrophic calcification.
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
--- Content provided by FirstRanker.com ---
c) A is correct R is incorrectd) A is incorrect R is correct
xiv. (A): Gandy Gamna Bodies are seen in chronic venous congestion of Spleen
(R): Chronic venous congestion of spleen causes right sided heart failure.
a) Both A & R are correct and R is the reason for A
--- Content provided by FirstRanker.com ---
b) Both A & R are correct but R is not reason for Ac) A is correct R is incorrect
d) A is incorrect R is correct
xv. (A): von Willebrand factor is synthesized by Hepatocytes
(R): von Willebrand factor is a carrier protein for factor VIII
--- Content provided by FirstRanker.com ---
a) Both A & R are correct and R is the reason for Ab) Both A & R are correct but R is not reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
Question Numbers xvi? xx are based on case scenarios. Read the statements and mark the answers
--- Content provided by FirstRanker.com ---
accordingly.A 26 year old women with third degree burns developed septic shock. With 24hours she was bleeding from all
needle puncture sites, with extensive ecchymoses and petechiae and GI Bleeding. Lab studies showed Hb-
6gm/dl., platelet count 64000/cu mm., PT 20 seconds, PTT 50 seconds and D-dimer Positive.
xvi. What is your most probable clinical diagnosis
--- Content provided by FirstRanker.com ---
a) Acute Leukaemiab) Immune thrombocytopenia
c) Disseminated Intravascular coagulation
d) Anaphylactic shock
xvii. Which one of the following investigation is diagnostic
--- Content provided by FirstRanker.com ---
a) Platelet Countb) Prothrombin time c) Thrombin Time
d) D ? dimer test
xviii. The drop in the amount of Hemoglobin is mostly due to
a) Ineffective erythropiesis
--- Content provided by FirstRanker.com ---
b) Acute blood lossc) Aplasia of the marrow
d) Nutritional deficiency
xix. The most common morphology of red blood cells seen in the peripheral smear of the above case is
a) Microcytes
--- Content provided by FirstRanker.com ---
b) Schistocytesc) Drepanocytes
d) Codocytes
xx. Fibrin degradation products have
a) Potent anticoagulant effect
--- Content provided by FirstRanker.com ---
b) Platelet aggregation effectc) Prothrombotic effect
d) Endothelial activation effect
Long Essays.
--- Content provided by FirstRanker.com ---
(2x10=20)
2. A 50 year old person was admitted to the hospital with complaints of intermittent fever for the past two
--- Content provided by FirstRanker.com ---
weeks. He underwent a surgical procedure. The surgical wound has not healed. On examination Febrile,Pulse rate ? 102/mt, dyspnoea present, drowsy, urine output less than 100ml/ 24 hours. Blood sample
sent for culture and sensitivity. CBC ? Hemoglobin 8g/dl, total WBC count -18000/cmm.
a) What is your provisional diagnosis
b) Describe briefly the etiopathogenesis of this condition
--- Content provided by FirstRanker.com ---
c) What are the various organ changes seen in this conditiond) Enlist the stages of this condition
(2+3+3+2)
3. Define Leukaemia. Classify Acute Myeloblastic Leukaemia as per WHO classification. Describe the
peripheral smear and bone marrow findings with illustrations in a case of Acute Myeloid Leukaemia.
--- Content provided by FirstRanker.com ---
(2+3+2+3)Short Essays.
(6X6=36)
4. Type II hypersensitivity reaction
5. Role of Chemical Carcinogens
--- Content provided by FirstRanker.com ---
6. Laboratory Diagnosis of Thalassemia7. Granulomatous inflammation
8. Opportunistic Infections
9. Factors Influencing Wound Healing
Short Answers.
--- Content provided by FirstRanker.com ---
(6x4=24)10. Enlist two common indications and two absolute contraindications for bone marrow aspiration study
11. Enumerate four common laboratory tests done to confirm Multiple Myeloma
12. Enlist Four common types of Necrosis with suitable clinical examples
13. Name the four cardinal principles of Biomedical Ethics
--- Content provided by FirstRanker.com ---
14. Enlist four common anticoagulants used in a Hematology laboratory15. Mention four common stains used to demonstrate Amyloid in the tissues
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