Download KUHS MBBS 2nd Year 214001 Pathology Paper II Aug 2025 Question Paper

2019 Scheme
Q.P. Code: 214001
Reg. no.: .....................
Second Professional MBBS Degree Regular/Supplementary Examinations
August 2025

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Pathology - Paper II
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space

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Answer all parts of a single question together ? Leave sufficient space between answers
Draw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(20x1=20)
The responses for MCQ questions (Q.No. i to Q.No. xx) shall be written in the space provided for

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answering MCQ questions at page No. 51 of the answer book (the inner portion of the back cover
page (PART III)). Responses for MCQs marked in any other part/page of the answer book will not be
valued
Question Numbers (i) ? (v) are Single Response Type
i. Codman triangle is a radiological finding in:

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a) Multiple myeloma
b) Osteosarcoma
c) Chondrosarcoma
d) Ewings sarcoma
ii. Primary type II hyperlipidaemia (familial hypercholesterolemia) results from a defect in

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a) Lipoprotein lipase
c) Apolipoprotein E
b) Low-density lipoprotein (LDL) receptor
d) Apolipoprotein CII
iii. The most common histologic type of carcinoma of the oral cavity is

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a) Adenocarcinoma
c) Small cell carcinoma
b) Clear cell carcinoma
d) Squamous cell carcinoma
iv. Immune complexes located within the glomerular basement membrane would most

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likely be
found in a patient with
a) IgA nephropathy
b) Membranous G
N

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c) Minimal change diseas
e
d) Type II membranoproliferative glomerulonephritis (MPGN)
v. Which of the following testicular tumors is most radiosensitiv
e

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a) Seminoma
c) Choriocarcinoma
b) Embryonal carcino
ma
d) Yolk sac tumor

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Question numbers (vi)-(x) are multiple response type questions. Read the statements & mark the
answers appropriately.
vi
. Aortic dissection is associated with:
:

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1) Alports syndrome 2) Ehler's Danios syndrome
3) Marfan syndrome
4) Tumer's syndrom
e
a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1

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d) 4, 1, 2
vii. Following are germ cell tumours
1) Dysgermino
ma
2) Teratoma 3) Granulosa cell tumour 4) Yolk sac tumou

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r
a) 1, 2, 3
b) 2, 3, 4 c) 3, 4, 1 d) 4, 1, 2
viii. Malignant tumours include
s.

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1) Osteosarcoma 2) Osteoid osteoma 3) Chondrosarcoma 4) Ewing sarcoma
a) 1, 2, 3 b) 2, 3, 4
c) 3, 4, 1 d) 4, 1, 2
ix. Chronic bronchitis is characterised by
1) Smooth muscle hypertrophy 2) leucocyte infiltration 3) Mucus gland hypertrophy

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4) Curschman spirals
a) 1, 2, 3
b) 2, 3, 4 c) 3, 4, 1 d) 4, 1, 2
x. Premalignant lesion of oral cavity includes
1) leukoplakia 2) Aphthous ulcer 3) Squamous cell carcinoma insitu 4) Erythroplakia

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a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1 d) 4, 1, 2

(PTO
)

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Question numbers (xi) ? (xv) consists of two Statements - Assertion (A) and Reason (R). Answer
these questions by selecting the appropriate options given below.
a) Both A & R are correct and R is the reason for A

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c) A incorrect & R is correct
b) Both A & R are correct and R is not reason for A
d) A is correct but R is not correct
xi. Assertion: Gall stones are more common in females
Reason: Hypersecretion of cholesterol in bile plays major role in gender difference

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xii. Assertion: Left and right-side colonic carcinoma gross presentation differs
Reason: Because left and right-side colonic carcinoma differs microscopically
xiii. Assertion: Nephrotic syndrome is characterized by selective massive proteinuri
a
Reason: Minimal change disease is caused effacement of foot process

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xiv
. Assertion: HPV infection is associated with carcinoma cervix
Reason: All HPV infection proceeds to High grade squamous intraepithelial lesion
xv
. Assertion: Psoriasis is a chronic inflammatory dermatosi

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s
Reason: It is characterized by autoimmune mediated keratinocyte proliferation
Question numbers (xvi) ? (xx) Read the following case scenario and answer subsequent
questions based on this
A 42-year-old man presents because recently he had to change his shoe size from 9 to 10.5. He also

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says that his hands and jaw are now larger.
xvi
.
Disorder is most likely mediated through the actions of excess
a) Prolactin

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b) ACTH
c) Somatostatin
d) Antidiuretic hormon
e
xvii. Above condition associated with increased size of

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a) Heart
b) Kidneys
c) Liver
d) All the above
xviii. Most likely diagnosis

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a) Acromegaly
b) Cushing's syndrome
c) Prolactinoma
d) Sheehan's syndrome
xix. Which of the following disease is not associated with above condition

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a) Diabetes
b) Hypertension
c) Cardiomyopathy d) Hypotension
xx. Which of the following is NOT a anterior pituitary hormone
a) FSH

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b) Prolactin
c) Oxytocin d) LH

Long Essays

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(2x10=20)
2. A 50 years old man collapses suddenly while climbing the stairs with severe chest pain and profuse

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sweating.
a) What is your clinical diagnosis
b) Discuss the aetiopathogenesis of the condition
c) What are the complications that may follow the condition
(1+5+4)

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3. Define and Classify cirrhosis of liver, write in detail about alcoholic cirrhosis
(1+4+5)
Short Essays
(6x6=36)
4. Pathology of Seminoma Testis

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5. Classify ovarian neoplasms. Discuss in brief about surface epithelial tumours
6.
Prognostic and predictive factors of breast cancer.
7. Hashimoto's thyroiditis
8. Precancerous lesions of skin

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9. Giant cell tumor bon
e
Short Answers

(6x4=24

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)
10. Explain Do not resuscitate
11. Good Pasteur's syndrome ? pathogenesis and patholog
y
12. Pleomorphic adenom

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a
13. CSF in TB meningitis
14. Four pathological effects of gall stones
15. Intestinal polyps
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