2019 Scheme
Q.P. Code: 214001
Reg. no.: .....................
Second Professional MBBS Degree Supplementary (SAY) Examinations
March 2025
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space
Draw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(20x1=20)
The MCQ questions (Q.No. i to Q.No. xx) shall be written in the space provided for answering MCQ
Responses for MCQs marked in any other part/page of the answer book will not be valued
Question Numbers (i) ? (v) are Single Response Type
i. Presence of tumour cells in an Indian file pattern is typical of
a) Invasive lobular carcinoma
b) Medullary carcinoma
d) Cribriform carcinoma
ii. All are true about carcinoma endometrium EXCEPT
a) Commonly seen in post menopausal women
c) Endometrioid type is associated with increased signaling through P13K/AKT pathway
d) Serous carcinoma is aggressive than endometrioid type
iii. Reid index is diagnostic of
a) Chronic bronchitis
c) Bronchial asthma
d) Pneumonia
iv. Duke's criteria is often used in the diagnosis
a) Infective endocarditis
b) Rheumatic Heart Disease
d) Ischaemic Heart disease
v. All are true about malignant melanoma EXCEPT
a) It has radial and vertical growth phase
c) Metastatic deposits show black colour
d) Peripheral palisading of tumour cell Nests are seen in microscopic sections
Question numbers (vi)-(x) are multiple response type questions. Read the statements & mark
the answers appropriately.
1) Associated with HLADR3, HLADR4 or both
2) Autoimmune destruction of cells occurs
3) Most common in childhood
4) Associated with central obesity
c) 1, 3 and 4 are correct
b) 2, 3 and 4 are correct
d) 1, 2 and 4 are correct
vii. Epstein Barr Virus is associated with the following cancers
2) Nasopharyngeal Carcinoma
3) Gastric carcinoma
4) Hodgkin's Lymphoma
a) 1, 2 and 3 are correct
b) 2, 3 and 4 are correct
d) 1, 2 and 4 are correct
viii. Features of Helicobacter pylori infection
1) It produces antral gastritis
3) It invades the gastric mucosa
4) Warthin starry stain is used to demonstrate it
a) 1, 2 and 3 are correct
c) 1, 3 and 4 are correct
d) 1, 2 and 4 are correct
ix. Small blue round cell tumours include
1) Retinoblastoma
2) Ewing's sarcoma 3) Cholangiocarcinoma
a) 1, 2 and 3 are correct
c) 1, 3 and 4 are correct
b) 2, 3 and 4 are correct
d) 1, 2 and 4 are correct
x. Glomerular alterations in diabetic nephropathy includes
1) Thickening of the basement membrane
2) Nodular Glomerulosclerosis
4) Armani Epstein lesion
a) 1, 2 and 3 are correct
c) 1, 3 and 4 are correct
b) 2, 3 and 4 are correct
Question numbers (xi) ? (xv) consists of two Statements - Assertion (A) and Reason (R).
Answer these questions by selecting the appropriate options given below.
xi. (A) Prophylactic colectomy is to be done in all patients with Familial Adenomatous Polyposis
(FAP)
a) Both A & R are correct and R is the reason for A
c) A is correct R is incorrect
b) Both A & R are correct but R is not reason for A
d) A is incorrect R is correct
(R) E-cadherin expression is lost in intestinal type of gastric adenocarcinoma
a) Both A & R are correct and R is the reason for A
c) A is correct R is incorrect
b) Both A & R are correct but R is not reason for A
xiii. (A) Hepatitis E virus is the most common cause for transfusion associated Hepatitis
(R) Hepatitis E infection in pregnancy carries higher mortality
a) Both A & R are correct and R is the reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
xiv. (A) Psammoma bodies are seen in cases of papillary carcinoma thyroid
(R) Dystrophic calcification of tumour necrosis produces Psammoma bodies
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
d) A is incorrect R is correct
xv. (A) Charcot Leyden Crystals are seen in sputum of patients with Bronchial Asthma
(R) Remodeling of the bronchial wall occurs in cases of Bronchial Asthma
c) A is correct R is incorrect
b) Both A & R are correct but R is not reason for A
d) A is incorrect R is correct
Question numbers (xvi) ? (xx) Read the following case scenario and answer subsequent
A 58 year old female presented the surgical OPD with a lump in her right breast ? 3 weeks. No pain
or sudden increase in size O/E Solitary, ill-defined firm to hard nodular mass in the outer upper
quadrant of breast. Examination of right axillary region shows four palpable nodes. contralateral
breast is normal.
a) Tumour cells forming tubules and irregular sheets
b) Nuclear pleomorphism and numerous mitosis
c) Malignant cells separated by dense fibrous stroma
d) Ducts lined by epithelial and myoepithelial cells and stroma proliferating circumferentially
a) MRI scan
c) Mammogram
b) Clinical Examination
d) Fine Needle Aspiration Cytology
a) Tumour grade
c) Hormone Receptor status
b) Axillary Lymphnode status
d) Parity status
a) Tubular carcinoma
c) Medullary carcinoma
b) Lobular carcinoma
d) Mucinous carcinoma
a) More common in young women
b) Metastasize early to viscera and brain
c) Targeted therapy available
d) Most common carcinoma associated with BRCA 2 germline mutation
Long Essays
(2x10=20)
2. A 6 year old school going boy was brought by his father to the Paediatric OPD with complaints of
swelling in the face and leg for the past one week with passing of reduced amount of high
detected and treated in his school health programme. On examination the boy is under
nourished, periorbital edema present, pedal edema present. His Blood pressure was 130/100
mm of Hg.Pulse rate was 94/mt regular.
a) What is your provisional diagnosis
c) List the investigations and their interpretations to support your diagnosis
d) What is the prognosis of this condition
e) Enumerate the common complication of this condition
(1+4+4+1)
microscopic features of myocardial infarction. Add a note on the complications
(4+3+3)
Short Essays (6x6=36)
4. Pathogenesis and morphology of Emphysema
6. Pathology of Seminoma testis
7. Alcoholic liver disease
8. Hodgkin's lymphoma
9. Pathogenesis and screening methods of carcinoma cervix
10. Germ cell tumours of Ovary
11. Meningioma
12. Enlist four common situations in which the Confidentiality principle of Bioethics could be
breached
14. Compare and contrast four important microscopic features of Crohn's disease and Ulcerative
Colitis
15. Osteoclastoma
***************************
Q.P. Code: 214001
Reg. no.: .....................
Second Professional MBBS Degree Supplementary (SAY) Examinations
March 2025
--- Content provided by FirstRanker.com ---
Pathology - Paper IITime: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space
--- Content provided by FirstRanker.com ---
Answer all parts of a single question together ? Leave sufficient space between answersDraw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(20x1=20)
The MCQ questions (Q.No. i to Q.No. xx) shall be written in the space provided for answering MCQ
--- Content provided by FirstRanker.com ---
questions at page No. 51 of the answer book (the inner portion of the back cover page (PART III)).Responses for MCQs marked in any other part/page of the answer book will not be valued
Question Numbers (i) ? (v) are Single Response Type
i. Presence of tumour cells in an Indian file pattern is typical of
a) Invasive lobular carcinoma
--- Content provided by FirstRanker.com ---
c) Papillary carcinomab) Medullary carcinoma
d) Cribriform carcinoma
ii. All are true about carcinoma endometrium EXCEPT
a) Commonly seen in post menopausal women
--- Content provided by FirstRanker.com ---
b) Unopposed estrogen stimulation leads to serous carcinomac) Endometrioid type is associated with increased signaling through P13K/AKT pathway
d) Serous carcinoma is aggressive than endometrioid type
iii. Reid index is diagnostic of
a) Chronic bronchitis
--- Content provided by FirstRanker.com ---
b) Emphysemac) Bronchial asthma
d) Pneumonia
iv. Duke's criteria is often used in the diagnosis
a) Infective endocarditis
--- Content provided by FirstRanker.com ---
c) Cardiomyopathyb) Rheumatic Heart Disease
d) Ischaemic Heart disease
v. All are true about malignant melanoma EXCEPT
a) It has radial and vertical growth phase
--- Content provided by FirstRanker.com ---
b) Spontaneous regression of primary tumour may occurc) Metastatic deposits show black colour
d) Peripheral palisading of tumour cell Nests are seen in microscopic sections
Question numbers (vi)-(x) are multiple response type questions. Read the statements & mark
the answers appropriately.
--- Content provided by FirstRanker.com ---
vi. Type I diabetes mellitus1) Associated with HLADR3, HLADR4 or both
2) Autoimmune destruction of cells occurs
3) Most common in childhood
4) Associated with central obesity
--- Content provided by FirstRanker.com ---
a) 1, 2 and 3 are correctc) 1, 3 and 4 are correct
b) 2, 3 and 4 are correct
d) 1, 2 and 4 are correct
vii. Epstein Barr Virus is associated with the following cancers
--- Content provided by FirstRanker.com ---
1) Endometrial Carcinoma2) Nasopharyngeal Carcinoma
3) Gastric carcinoma
4) Hodgkin's Lymphoma
a) 1, 2 and 3 are correct
--- Content provided by FirstRanker.com ---
c) 1, 3 and 4 are correctb) 2, 3 and 4 are correct
d) 1, 2 and 4 are correct
viii. Features of Helicobacter pylori infection
1) It produces antral gastritis
--- Content provided by FirstRanker.com ---
2) It releases ammonia from endogenous urea3) It invades the gastric mucosa
4) Warthin starry stain is used to demonstrate it
a) 1, 2 and 3 are correct
c) 1, 3 and 4 are correct
--- Content provided by FirstRanker.com ---
b) 2, 3 and 4 are correctd) 1, 2 and 4 are correct
ix. Small blue round cell tumours include
1) Retinoblastoma
2) Ewing's sarcoma 3) Cholangiocarcinoma
--- Content provided by FirstRanker.com ---
4) Neuroblastomaa) 1, 2 and 3 are correct
c) 1, 3 and 4 are correct
b) 2, 3 and 4 are correct
d) 1, 2 and 4 are correct
--- Content provided by FirstRanker.com ---
(PTO)x. Glomerular alterations in diabetic nephropathy includes
1) Thickening of the basement membrane
2) Nodular Glomerulosclerosis
--- Content provided by FirstRanker.com ---
3) Diffuse Glomerulosclerosis4) Armani Epstein lesion
a) 1, 2 and 3 are correct
c) 1, 3 and 4 are correct
b) 2, 3 and 4 are correct
--- Content provided by FirstRanker.com ---
d) 1, 2 and 4 are correctQuestion numbers (xi) ? (xv) consists of two Statements - Assertion (A) and Reason (R).
Answer these questions by selecting the appropriate options given below.
xi. (A) Prophylactic colectomy is to be done in all patients with Familial Adenomatous Polyposis
(FAP)
--- Content provided by FirstRanker.com ---
(R) Minimum 100 polyps are necessary for the diagnosis of FAPa) Both A & R are correct and R is the reason for A
c) A is correct R is incorrect
b) Both A & R are correct but R is not reason for A
d) A is incorrect R is correct
--- Content provided by FirstRanker.com ---
xii. (A) Intestinal type of gastric adenocarcinoma present as polypoid bulky tumour(R) E-cadherin expression is lost in intestinal type of gastric adenocarcinoma
a) Both A & R are correct and R is the reason for A
c) A is correct R is incorrect
b) Both A & R are correct but R is not reason for A
--- Content provided by FirstRanker.com ---
d) A is incorrect R is correctxiii. (A) Hepatitis E virus is the most common cause for transfusion associated Hepatitis
(R) Hepatitis E infection in pregnancy carries higher mortality
a) Both A & R are correct and R is the reason for A
c) A is correct R is incorrect
--- Content provided by FirstRanker.com ---
b) Both A & R are correct but R is not reason for Ad) A is incorrect R is correct
xiv. (A) Psammoma bodies are seen in cases of papillary carcinoma thyroid
(R) Dystrophic calcification of tumour necrosis produces Psammoma bodies
a) Both A & R are correct and R is the reason for A
--- Content provided by FirstRanker.com ---
c) A is correct R is incorrectb) Both A & R are correct but R is not reason for A
d) A is incorrect R is correct
xv. (A) Charcot Leyden Crystals are seen in sputum of patients with Bronchial Asthma
(R) Remodeling of the bronchial wall occurs in cases of Bronchial Asthma
--- Content provided by FirstRanker.com ---
a) Both A & R are correct and R is the reason for Ac) A is correct R is incorrect
b) Both A & R are correct but R is not reason for A
d) A is incorrect R is correct
Question numbers (xvi) ? (xx) Read the following case scenario and answer subsequent
--- Content provided by FirstRanker.com ---
questions based on thisA 58 year old female presented the surgical OPD with a lump in her right breast ? 3 weeks. No pain
or sudden increase in size O/E Solitary, ill-defined firm to hard nodular mass in the outer upper
quadrant of breast. Examination of right axillary region shows four palpable nodes. contralateral
breast is normal.
--- Content provided by FirstRanker.com ---
xvi. Microscopy of this lesion will show all EXCEPTa) Tumour cells forming tubules and irregular sheets
b) Nuclear pleomorphism and numerous mitosis
c) Malignant cells separated by dense fibrous stroma
d) Ducts lined by epithelial and myoepithelial cells and stroma proliferating circumferentially
--- Content provided by FirstRanker.com ---
xvii. Which one of the following is NOT included in the triple assessment of breast lumpsa) MRI scan
c) Mammogram
b) Clinical Examination
d) Fine Needle Aspiration Cytology
--- Content provided by FirstRanker.com ---
xviii. All of the following are prognostic parameters in the evaluation of Breast Carcinoma EXCEPTa) Tumour grade
c) Hormone Receptor status
b) Axillary Lymphnode status
d) Parity status
--- Content provided by FirstRanker.com ---
xix. Morphologic type of invasive carcinoma breast with excellent prognosisa) Tubular carcinoma
c) Medullary carcinoma
b) Lobular carcinoma
d) Mucinous carcinoma
--- Content provided by FirstRanker.com ---
xx. All are true statement about HER2 positive invasive carcinoma breast EXCEPTa) More common in young women
b) Metastasize early to viscera and brain
c) Targeted therapy available
d) Most common carcinoma associated with BRCA 2 germline mutation
--- Content provided by FirstRanker.com ---
(PTO)Long Essays
--- Content provided by FirstRanker.com ---
(2x10=20)
2. A 6 year old school going boy was brought by his father to the Paediatric OPD with complaints of
swelling in the face and leg for the past one week with passing of reduced amount of high
--- Content provided by FirstRanker.com ---
coloured urine since 3 days. The father also gave a past history of the boy having scabies,detected and treated in his school health programme. On examination the boy is under
nourished, periorbital edema present, pedal edema present. His Blood pressure was 130/100
mm of Hg.Pulse rate was 94/mt regular.
a) What is your provisional diagnosis
--- Content provided by FirstRanker.com ---
b) Aetiopathogenesis of this conditionc) List the investigations and their interpretations to support your diagnosis
d) What is the prognosis of this condition
e) Enumerate the common complication of this condition
(1+4+4+1)
--- Content provided by FirstRanker.com ---
3. Discuss in detail the pathogenesis of acute myocardial infarction. Discuss the gross andmicroscopic features of myocardial infarction. Add a note on the complications
(4+3+3)
Short Essays (6x6=36)
4. Pathogenesis and morphology of Emphysema
--- Content provided by FirstRanker.com ---
5. Pathogenesis and Pathology of Hashimoto's Thyroiditis6. Pathology of Seminoma testis
7. Alcoholic liver disease
8. Hodgkin's lymphoma
9. Pathogenesis and screening methods of carcinoma cervix
--- Content provided by FirstRanker.com ---
Short Answers (6x4=24)10. Germ cell tumours of Ovary
11. Meningioma
12. Enlist four common situations in which the Confidentiality principle of Bioethics could be
breached
--- Content provided by FirstRanker.com ---
13. Pleomorphic adenoma14. Compare and contrast four important microscopic features of Crohn's disease and Ulcerative
Colitis
15. Osteoclastoma
***************************
--- Content provided by FirstRanker.com ---