2019 Schem
e
Q.P. Code: 215001
Reg. no.: .....................
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Second Professional MBBS Degree Regular/Supplementary ExaminationsAugust 202
5
Microbiology Paper
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ITime: 3 Hour
s
Total Marks: 10
0
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Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answersIndicate the question number correctly for the answer in the margin spac
e
Answer all parts of a single question together ? Leave sufficient spac
e between answers
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Draw table/diagrams/flow charts wherever necessary
1. Multiple Choice Question
s
(20x1=20
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)The responses for MCQ questions (Q.No. i to Q.No. xx) shall be written in the space provided for
answering MCQ questions at page No. 51 of the answer book (the inner portion of the back
cover page (PART III)). Responses for MCQs marked in any other part/page of the answer book
will not be value
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dRead the following clinical history and select the most appropriate response for questions (i) -(v)
A 25 years old lady came to surgical OP with complaints of fever pain and swelling of the breast of 3 days
duration. Gram stain of pus aspirate revealed gram positive cocci along with pus cell
s.
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i. What is the most probable organism
a) Staphylococcus
b) Streptococcu
s
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c) Enterococcus
d) Pneumococcu
s
ii. Name the biochemical test to identify the pathogenic specie
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sa) Catalase
b) Coagula
se
c) Oxidase
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d) Nitrate test
iii. Drug of choice for the sensitive organism
a) Vancomyci
n
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b) Linezolid
c) Teicoplani
n
d) Coxacillin
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iv. An example of toxin mediated disease caused by this organism
a) Impelig
o
c) Staphylococcal Scalded Skin Syndrom
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eb) Osteomyeliti
s
d) Urinary tract infectio
n
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v. Toxin responsible for the above condition
a) Epidermolytic toxin
c) Enterotoxi
n
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b) Toxic shock syndrome toxind) Haemolytic toxin
Question numbers (vi)-(x) are multiple response type questions. Read the statements & mark the
answers appropriately.
vi. All are true about bacterial spore
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s1) They are the method of reproductio
n
2) They are resistant to dessicatio
n
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3) They can be destroyed by autoclaving at 1200C for 15 minutes
4) They are produced by the genus Bacillu
s
a) 1, 2 & 3 are correct
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c) 1, 2 & 4 are correctb) 1, 3 & 4 are correct
d) 2, 3 & 4 are correct
vii. Examples of enrichment media are
1) Selenite F broth
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2) Tetra thionate broth3) Glucose broth
4) Brain heart infusion broth
a) 1 & 2 are correct
c) 2, 3 & 4 are correct
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b) 2 & 3 are correct
d) 1, 3 & 4 are correct
viii.
Examples of broad spectrum antibiotics are
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1) Tetracycline 2) Gentamicin 3) Ciprofloxacin 4) Caftnaxonea) 1, 2 & 3 are correct
c) 2, 3 & 4 are correct
b) 1, 3 & 4 are correct
d) 1, 2, 3 & 4 are correct
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ix. Examples of RNA viruses are1) Enterovirus 2) Influenza virus
3) Measles virus 4) Herpes virus
a) 1, 2 & 3 are correct
c) 3 & 4 are correct
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b) 1, 3 & 4 are correctd) 1, 2, 3 & 4 are correct
x. All are continuous cell line cultures
1) Human carcinoma of cervix cell line
2) Rhesus monkey kidney cell culture
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3) Human epithelioma of larynx cell line4) Human embryonic kidney cell strain
a) 1 & 2 are correct
c) 3 & 4 are correct
b) 1 & 3 are correct
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d) 2 & 4 are correct(PTO)
Question numbers (xi) ? (xv) are single response types
xi. Malaria is transmitted by
a) Culex mosquito
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b) Anophales mosquitoc) Aedes mosquito
d) All of the above
xii. Trypanosoma cruzei causes
a) Chagas disease
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c) West African sleeping sicknessb) East African sleeping sickness
d) Kalaazar
xiii. Lymphatic filariasis is caused by
a) Wuchereria bancrofti b) Brugia malayi
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c) Brugia timorid) All of the above
xiv. Guinea worm disease is acquired by the ingestion of contaminated water containing
a) Embryonated eggs
b) Cyclops
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c) Adult worm d) Free swimming larvaxv. An example of systemic mycosis is
a) Sporotrichosis
b) Rhinosporidiosis
c) Histoplasmosis d) Chromoblastomycosis
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Question numbers (xvi) ? (xx) consists of two Statements-Assertion (A) and reason (R). Answer thesequestions by selecting the appropriate options given below.
a) Both A and R are true and R is the correct explanation of A
c) A is true and R is false
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b) Both A and R are true and R is not the correct explanation of Ad) A is false but R is true
xvi. Assertion: Bronchoscopes are sterilized by high level sterilants
Reason: Bronchoscopes are critical instruments
xvii. Assertion: Viral envelope is lipoprotein in nature
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Reason: Enveloped viruses are highly resistantxviii. Assertion: Dimorphic fungi grows as filamentous form at 220C
Reason: Histoplasma capsulatum belongs to dimorphic fungi
xix. Assertion: Pityriasis versicolor is a subcutaneous mycoses
Reason: Malassezia furfur is the causative agent for Pityriasis versicolor
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xx. Assertion: Autoclave is an example of moist heat method of sterilizationReason: Steam is the sterilizing agent in autoclave
Essays
(2x10=20)
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2. A 32 year old man admitted to hospital with cellulitis of the left arm following fever for 15 days. Onexamination, he was emaciated and had pallor. Physical examination revealed multiple needle stick
marks on his upper and lower limbs. He had splinter hemorrhage and splenomegaly. Auscultation
revealed a systolic murmur on left sternal border.
a) What is the probable diagnosis.
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b) What are the organisms responsible for the disease.c) Lab diagnosis of the above condition and add a note on Duke's criteria.
(1+4+5)
3. A 10 years old child came to paediatric OP with complaints of fever and erythematous rashes of 4 days
duration. His platelet count was 20000.
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a) What is your provisional diagnosis.b) Name the causative organisms.
c) Discuss the pathogenesis of this condition.
d) How do you confirm the clinical diagnosis.
e) Discuss the management of the patient.
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f) Briefly describe the prophylaxis.(1+2+2+3+1+1)
Short Essays
(6x6=36)
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4. Discuss horizontal gene transfer methods and its clinical significance.5. Name all the species of malarial parasites and write the life cycle of Plasmodium vivax.
(2+4)
6. What are the causative agents of mycotic mycetoma. Write about the clinical features and laboratory
diagnosis of mycotic mycetoma.
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(1+2+3)7. Explain the ethical rule of autonomy.
8. Classify immunity and add a note on passive immunity with examples.
(2+4)
9. Draw a neat diagram of Immunoglobulin A (Ig A) and write a short essay on IgA.
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(2+4)Short Answers
(6x4=24)
10. Discuss NACO strategy III.
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11. Classify hypersensitivity reactions and add a note on type IV hypersensitivity reaction.(1+3)
12. Enumerate healthcare associated infections and one causative organism. (2+2)
13. Write in brief about biomedical waste management.
14. Define enriched media. Give THREE examples.
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15. Name FOUR gaseous disinfectants.***************************