Download KUHS MBBS 2nd Year 216001 Microbiology Paper II Aug 2025 Question Paper

2019 Scheme
Q.P. Code: 216001
Reg. no.: .....................
Second Professional MBBS Degree Regular/Supplementary Examinations
August 2025

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Microbiology Paper II
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space

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Answer all parts of a single question together ? Leave sufficient space between answers
Draw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(20x1=20)
The responses for MCQ questions (Q.No. i to Q.No. xx) shall be written in the space provided for

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answering MCQ questions at page No. 51 of the answer book (the inner portion of the back
cover page (PART III)). Responses for MCQs marked in any other part/page of the answer book
will not be valued
Read the following clinical history and select the most appropriate response for questions i - v
A 5 year old girl presented to paediatric O P with complaints of fever and loose stools for one day. Mother

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noticed presence of blood in stool. Stool microscopy showed no motile trophozoites. Plenty of pus cells and
RBC were seen
i. What is your provisional diagnosis
a) Bacillary dysentry
c) Viral gastroenteritis

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b) Amoebic dysentery
d) Giardiasis
ii. Most common causative agent
a) Entamoeba
b) Shigell

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a
c) Giardia
d) Rota viru
s
iii. Virulence mechanism of the above condition

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a) Invasion
b) Preformed toxi
n
c) Endo toxin d) Capsul
e

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iv. Enrichment medium used for stool cultur
e
a) Glucose broth
c) Selenite F brot
h

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b) Brain heart Infusion brot
h
d) Carry Blair mediu
m
v. Name the complication following the above conditio

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n
a) Liver abscess
c) Ulceration of the small intestin
e
b) Empyem

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a
d) Haemolytic uraemic syndrom
e
Question numbers vi
- x are multiple response type questions. Read the statements & mark the

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answers appropriately.
vi. Specific serological test for laboratory diagnosis of Streptococcal sore throat is
,
1) Anti-Streptolysin O test (ASO test)
2) C-reactive protein(CRP) te

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st
3) Rheumatoid factor (RF) test 4) Anti-deoxyribonuclease tes
t
a) 1, 2 are correct
b) 1, 2, 3 are correct

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c) 1, 4 are correct
d) 3, 4 are correct
vii.
All are nematodes inhabiting in the small intestine
1) Ascari

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s lumbricoides
2) Trichuns trichur
a 3) Strongyloides stercoralis
4) Ancyclostoma duodenal
e

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a) 1, 2, 3 are correct
b) 2, 3, 4 are correct
c) 1, 3, 4 are correct
d) 1, 2, 3, 4 are corre
ct

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viii. Causative agents of acute viral meningitis is
1) Coxsackie viru
s
2) ECHO viru
s 3) Mumps viru

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s
4) Varicella zoster viru
s
a) 1, 2, 3, 4 are correct b) 1, 2, 3 are correct
c) 2, 3, 4 are correct

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d) 1, 3, 4 are correct
ix. The family paramyxoviridae includes
1) Mumps virus 2) Rhinovirus 3) New castle disease virus 4) Respiratory syncytial virus
a) Only 2 is correct
b) 1, 2, 3 are correct

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c) 1, 4 are correct
d) 1, 3, 4 are correct
x. Amoebae causing diseases in humans are
1) Entamoeba histolytica 2) Entamoeba dispar 3) Acanthamoeba species 4) Entamoeba gingivalis
a) 1, 2 are correct

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b) 1, 3 are correct
c) 1, 4 are correct
d) 3, 4 are correct
Question numbers xi ? xv are single response types
xi. The stain not used for Corynebacterium is

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a) Albert b) Kinyoun
c) Ponder
d) Neisser
xii. The capsule of Streptococcus pneumoniae in CSF can be demonstrated by
a) India ink c) Precipitation with antisera

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b) Latex agglutination
d) All of the above
xiii. Primary agents of pyogenic meningitis includes all of the following EXCEPT
a) Streptococcus pneumoniae c) Neisseria meningitidis
b) Haemophilus influenzae

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d) Streptococcus agalactiae
(PTO)

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xiv. Informed consent include
s
a) Willing acceptance of a medical intervention by a patien

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t
b) Adequate disclosure by the doctor of the nature of interventio
n
c) Explanation about risks and benefits and also its alternative
s

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d) All of the abov
e
xv. Humans acquire Ancylostoma infection b
y
a) Ingestion of larva

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c) Penetration of skin by filiform larv
a
b) Ingestion of fertilised egg
d) Ingestion of either eggs or larv
a

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Question numbers xvi ? xx consists of two Statements-Assertion (A) and Reason (R). Answer these
questions by selecting the appropriate options given below.
a) Both A and R are true and R is the correct explanation of A c) A is true but R is false
b) Both A and R are true and R is not the correct explanation of A
d) A is false but R is true

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xvi. Assertion: Polio virus causes acute flaccid paralysi
s
Reason: Polio virus destroys anterior horn cells of spinal cor
d
xvii. Assertion: Influenza virus is a segmented RNA viru

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s
Reason: Influenza virus shows antigenic variabilit
y
xviii. Assertion: Pulmonary tuberculosis is diagnosed by Acid Fast Stainin
g

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Reason: Mycobacterium tuberculosis is the only acid fast Mycobacterium
xix. Assertion: Aspergillus is a dimorphic fungu
s
Reason: Aspergillus causes pulmonary infection
s

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xx. Assertion: Characteristic perianal itching is produced during night by Enterobius vermicular
is
Reason: NIH swab is used for the diagnosis of Enterobius vermicular
is.
Essays

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(2x10=20

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)
2. A 48-year-old lady presented with history of low grade evening rise of temperature and productive cough
for past 3 months. She also gave history of weight loss and loss of appetite. Chest x ray showed nodular
infiltrate in the apical area of the left lobe of the lung
a) What is the provisional diagnosi

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s
b) Discuss the laboratory diagnosis as per the national programme for elimination of the diseas
e
c) Name Four first line microbicidal drug
s

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d) Discuss the measures for elimination of this diseas
e
(1+4+2+3
)
3. A ten-year-old boy was bitten by a dog and later developed fever, headache, anxiety, agitation, and

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nervousness. He had difficulty in drinking water along with intense thirst. Attempt to drink water brought
painfull spasm of the pharynx and larynx with violent chocking. After few days he died
a) What is the disease in the above cas
e
b) Discuss the ante mortem and postmortem laboratory diagnosi

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s
c) Name Three non-neural vaccine
s
d) Discuss the pre and post exposure prophylaxis of this disease

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(1+3+3+3
)
Short Essays

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(6x6=36)
4. Name Four cestodes. Discuss in detail cysticercosi
s
5. Enumerate Four agents causing viral diarrhea. Discuss the pathogenesis,laboratory diagnos
is of anyone.

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(2+2+2)
6. Classify hepatitis virus. Write about the lab diagnosis and prophylaxis for hepatitis A virus
(1+3+2)
7.
A 40-year-old cattle rearer presented with abdominal pain for past one year with no history of vomiting,

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jaundice, fever or loss of weight. Abdominal ultrasound suggested cystic swelling in the liver. Total
leucocyte count was 8800/micro litre and eosinophil count was 6%. He was operated and cyst is removed
and it was sent for investigation. Characteristic hyline glasslike membrane filled with sand and fluid was
found.
a) What is the probable diagnosis

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b) Explain in brief the life cycle and lab d iagnosis of the etiological agent
(1+3+2)
8. Discuss in detail bacterial food poisoning
9. Name Four bacterial zoonosis. Discuss in detail any one of them

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(2+4)
Sh ort Answers
(
6x4=2 4)

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10. Give at least four examples for emerging infection. Add a note on Nip
ha virus
(2+2)
11. Name four examples
o f

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o
p
p
o
r

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t
u
n
i
st i

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c i
n
f
e
cti

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o
n i
n
H I
V

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p
o
s i t i
ve
p

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a t i
e
n t
s . Add a note on
cr

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y
p t
o
c
o

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cca l
meningitis
(2+2)
12. Enumerate congenital viral infection. A
dd a note on congenital cyto

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m
e
g
a l
o

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vi r
u
s infect ion
(2+2
)

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13. What are the four principal of b ioethics. Write about non malefi
ce
n
c
e

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(1+3)
14. Write the morphology, life cycle and lab diagnosi
s
o f
G

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i
a
r
d
i

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a
s i
s
(1+1+2)
15. Write in brief about the lab diagnosis of Diphtheria

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