2019 Scheme
Q.P. Code: 216001
Reg. no.: .....................
Second Professional MBBS Degree Supplementary Examinations
December 2025
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space
Draw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(20x1=20)
The MCQ questions (Q.No. i to Q.No. xx) shall be answered only in the OMR sheet provided at page
marked in any other part/page of the answer book will not be valued. For marking the correct responses
use X mark only
Read the following clinical history and select the most appropriate response for questions i - v
A 14-year-old unimmunised boy was presented to the medical OPD with c/o fever, malaise and difficulty in
i. The probable clinical diagnosis is
a) Mumps
b) Measles
c) Herpes
ii. The pathogenicity of this organism is due to
a) Exotoxin
b) Invasiveness
c) Endotoxin
iii. Which of the following is the culture media specifically used for isolating this organism
a) LJ medium
c) Brain Heart Infusion Broth
b) Sabouraud's Dextrose Agar
iv. Mention the protective titre following vaccination for this disease
a) >0.01 IU/ml
b) >0.1 IU/ml
c) 1 IU/ml
v. What is the mode of transmission of this disease
a) Skin contact
b) Blood transfusion c) Respiratory droplets
d) Mother to child
answers appropriately.
vi. Streptococcus pneumoniae shows positive to
1) Quellung reaction 2) Inulin fermentation 3) Optochin sensitivity
4) Bacitracin sensitivity
b) 1, 2, 3, 4 are correct
c) 2, 3, 4 are correct d) 1, 3, 4 are correct
vii. Clinically important cestodes
1) T.solium
3) T.trichiora
4) D.latum
a) 2, 3 are correct
b) 1, 2, 4 are correct
viii. Non neural Rabies vaccines are
1) Semple vaccine
2) BPL vaccine
3) Duck embryo vaccine
a) 3, 4 are correct
b) 2, 4 are correct
c) 1, 2 are correct
d) 1, 2, 3 are correct
1) Increased lymphocyte count (80-90%)
2) Sugar<40 mg%
3) Protein increased 200-600 mg%
4) CSF pressure ? highly increased
c) 1, 2, 4 are correct d) 2, 3, 4 are correct
x. Examples of mycotoxins are
1) Aflatoxin
2) Ergot alkaloids
4) Muscarine
a) 1, 2, 3, 4 are correct b) 1, 3, 4 are correct
c) 1, 4 are correct
d) 1, 2, 3 are correct
xi. Lung fluke is
a) P.westermanii
b) C.sinensis
c) F.buski
xii. Darling's disease is another name for
a) Sporotrichosis
b) Blastomycosis
c) Rhinosporidiosis
xiii. Cold agglutination test is diagnostic for infections caused by
a) Leigionella
b) Listeria
c) Mycoplasma
xiv. Causative agent for Infectious mononuclosis is
a) Adenovirus
b) Epstein Barr virus
c) Coxsackie virus
xv. Which of the following is INCORRECT for campylobacter jejuni infection
a) Causes dysentery
c) Diagnosed by Urea Breath test
b) Can precipitate Guillain ? Barre syndrome d) Primarily a zoonoses
(PTO)
Question numbers xvi ? xx consists of two Statements-Assertion (A) and Reason (R). Answer these
questions by selecting the appropriate options given below.
a) Both A and R are true and R is the correct explanation of A c) A is true but R is false
b) Both A and R are true and R is not the correct explanation of A d) A is false but R is true
xvi. Assertion (A): VDRL test is also called as Standard test for Syphils
xvii. Assertion (A): Drug of choice for atypical pneumonia is Macrolides
Reason (R): Atypical pneumonia is commonly caused by Mycoplasma pneumoniae.
xviii. Assertion (A): Alkaline peptone water is used as an enrichment medium for Vibrio cholerae
Reason (R): Alkaline peptone water has a pH of 8.6
Reason (R): C.neoformans is a Gram positive yeast
xx. Assertion (A): Ancylostoma duodenale usually causes hyper infection syndrome
Reason (R): Ancylostoma duodenale enters into human body through skin penetration
Essays
(2x10=20)
gives history of blood transfusion 06 months back.
a) What is your clinical diagnosis and name the etiological agent.
b) Describe the pathogenesis of this clinical condition.
c) Describe the lab diagnosis of this clinical condition.
(1+3+4+2)
3. A 3 year old girl child admitted with history of acute onset of fever, headache and vomiting. On
examination, neck stiffness was seen. Gram stain of CSF sample revealed few pus cells and Gram
positive cocci arranged in pairs
b) Enumerate other organisms that can cause similar clinical conditions.
c) Describe the laboratory diagnosis of this condition
d) Add a note on vaccines available to prevent this condition.
(2+2+4+2)
(6x6=36)
4. Recent methods in lab diagnosis of tuberculosis
5. Shigellosis
6. Hydatid cyst
8. Free living amoebae
9. Pathogenesis and lab diagnosis of Japanese encephalitis
Short Answers
(6x4=24)
11. Write a note on Ethical guidelines for proper handling of patient sample
12. Germ tube test ? procedure and clinical significance
13. Virulence factors of B - pertussis
14. Mention the organisms included in TORCH complex
***************************
CORRECTION / NO-CORRECTION FILE
QPCODE: 216001 Dated: 29-12-2025
Corrected as "T.trichiura"
Corrections/Modifications/Replacement of Questions if any shall be made available to all
students. Take the print out of the Correction File in such cases and distribute to all
students.
CONTROLLER OF EXAMINATIONS
Q.P. Code: 216001
Reg. no.: .....................
Second Professional MBBS Degree Supplementary Examinations
December 2025
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Microbiology Paper IITime: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space
--- Content provided by FirstRanker.com ---
Answer all parts of a single question together ? Leave sufficient space between answersDraw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(20x1=20)
The MCQ questions (Q.No. i to Q.No. xx) shall be answered only in the OMR sheet provided at page
--- Content provided by FirstRanker.com ---
No. 51 of the answer book (the inner portion of the back cover page (PART III)). Responses for MCQsmarked in any other part/page of the answer book will not be valued. For marking the correct responses
use X mark only
Read the following clinical history and select the most appropriate response for questions i - v
A 14-year-old unimmunised boy was presented to the medical OPD with c/o fever, malaise and difficulty in
--- Content provided by FirstRanker.com ---
swallowing. On examination a greyish white patch was seen in the pharynx and it bleeds on touchi. The probable clinical diagnosis is
a) Mumps
b) Measles
c) Herpes
--- Content provided by FirstRanker.com ---
d) Diphtheriaii. The pathogenicity of this organism is due to
a) Exotoxin
b) Invasiveness
c) Endotoxin
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d) All of the aboveiii. Which of the following is the culture media specifically used for isolating this organism
a) LJ medium
c) Brain Heart Infusion Broth
b) Sabouraud's Dextrose Agar
--- Content provided by FirstRanker.com ---
d) Tellurite Blood agariv. Mention the protective titre following vaccination for this disease
a) >0.01 IU/ml
b) >0.1 IU/ml
c) 1 IU/ml
--- Content provided by FirstRanker.com ---
d) 10 IU/mlv. What is the mode of transmission of this disease
a) Skin contact
b) Blood transfusion c) Respiratory droplets
d) Mother to child
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Question numbers vi - x are multiple response type questions. Read the statements & mark theanswers appropriately.
vi. Streptococcus pneumoniae shows positive to
1) Quellung reaction 2) Inulin fermentation 3) Optochin sensitivity
4) Bacitracin sensitivity
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a) 1, 2, 3 are correctb) 1, 2, 3, 4 are correct
c) 2, 3, 4 are correct d) 1, 3, 4 are correct
vii. Clinically important cestodes
1) T.solium
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2) H.nana3) T.trichiora
4) D.latum
a) 2, 3 are correct
b) 1, 2, 4 are correct
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c) 2, 3, 4 are correct d) 1, 2 are correctviii. Non neural Rabies vaccines are
1) Semple vaccine
2) BPL vaccine
3) Duck embryo vaccine
--- Content provided by FirstRanker.com ---
4) Tissue culture vaccinesa) 3, 4 are correct
b) 2, 4 are correct
c) 1, 2 are correct
d) 1, 2, 3 are correct
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ix. CSF features characteristic of pyogenic meningitis includes1) Increased lymphocyte count (80-90%)
2) Sugar<40 mg%
3) Protein increased 200-600 mg%
4) CSF pressure ? highly increased
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a) 1, 2, 3, 4 are correct b) 1, 3, 4 are correctc) 1, 2, 4 are correct d) 2, 3, 4 are correct
x. Examples of mycotoxins are
1) Aflatoxin
2) Ergot alkaloids
--- Content provided by FirstRanker.com ---
3) Ochratoxin4) Muscarine
a) 1, 2, 3, 4 are correct b) 1, 3, 4 are correct
c) 1, 4 are correct
d) 1, 2, 3 are correct
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Question numbers xi ? xv are single response typesxi. Lung fluke is
a) P.westermanii
b) C.sinensis
c) F.buski
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d) None of the abovexii. Darling's disease is another name for
a) Sporotrichosis
b) Blastomycosis
c) Rhinosporidiosis
--- Content provided by FirstRanker.com ---
d) Histoplasmosisxiii. Cold agglutination test is diagnostic for infections caused by
a) Leigionella
b) Listeria
c) Mycoplasma
--- Content provided by FirstRanker.com ---
d) Chlamydiaxiv. Causative agent for Infectious mononuclosis is
a) Adenovirus
b) Epstein Barr virus
c) Coxsackie virus
--- Content provided by FirstRanker.com ---
d) ECHO virusxv. Which of the following is INCORRECT for campylobacter jejuni infection
a) Causes dysentery
c) Diagnosed by Urea Breath test
b) Can precipitate Guillain ? Barre syndrome d) Primarily a zoonoses
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
(PTO)
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Question numbers xvi ? xx consists of two Statements-Assertion (A) and Reason (R). Answer these
questions by selecting the appropriate options given below.
a) Both A and R are true and R is the correct explanation of A c) A is true but R is false
b) Both A and R are true and R is not the correct explanation of A d) A is false but R is true
xvi. Assertion (A): VDRL test is also called as Standard test for Syphils
--- Content provided by FirstRanker.com ---
Reason (R): VDRL test is a specific test for Syphilisxvii. Assertion (A): Drug of choice for atypical pneumonia is Macrolides
Reason (R): Atypical pneumonia is commonly caused by Mycoplasma pneumoniae.
xviii. Assertion (A): Alkaline peptone water is used as an enrichment medium for Vibrio cholerae
Reason (R): Alkaline peptone water has a pH of 8.6
--- Content provided by FirstRanker.com ---
xix. Assertion (A): India Ink staining is used as a diagnostic test for Cryptococcal meningitisReason (R): C.neoformans is a Gram positive yeast
xx. Assertion (A): Ancylostoma duodenale usually causes hyper infection syndrome
Reason (R): Ancylostoma duodenale enters into human body through skin penetration
Essays
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(2x10=20)
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2. A 50 year male presents to medicine OPD with history of fever and jaundice of 02 months duration. Hegives history of blood transfusion 06 months back.
a) What is your clinical diagnosis and name the etiological agent.
b) Describe the pathogenesis of this clinical condition.
c) Describe the lab diagnosis of this clinical condition.
--- Content provided by FirstRanker.com ---
d) Add a note on drug therapy and prophylaxis of this disease.(1+3+4+2)
3. A 3 year old girl child admitted with history of acute onset of fever, headache and vomiting. On
examination, neck stiffness was seen. Gram stain of CSF sample revealed few pus cells and Gram
positive cocci arranged in pairs
--- Content provided by FirstRanker.com ---
a) What is your clinical diagnosis and the most likely etiological agent.b) Enumerate other organisms that can cause similar clinical conditions.
c) Describe the laboratory diagnosis of this condition
d) Add a note on vaccines available to prevent this condition.
(2+2+4+2)
--- Content provided by FirstRanker.com ---
Short Essays(6x6=36)
4. Recent methods in lab diagnosis of tuberculosis
5. Shigellosis
6. Hydatid cyst
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7. Mention 04 Bacterial Zoonotic Diseases. Add a note on Bubonic plague.8. Free living amoebae
9. Pathogenesis and lab diagnosis of Japanese encephalitis
Short Answers
(6x4=24)
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10. Clostridium difficle11. Write a note on Ethical guidelines for proper handling of patient sample
12. Germ tube test ? procedure and clinical significance
13. Virulence factors of B - pertussis
14. Mention the organisms included in TORCH complex
--- Content provided by FirstRanker.com ---
15. Draw a neat labelled diagram of trophozoite and cyst of Giardia lamblia***************************
CORRECTION / NO-CORRECTION FILE
QPCODE: 216001 Dated: 29-12-2025
--- Content provided by FirstRanker.com ---
Question No.1 (vii) (3)Corrected as "T.trichiura"
Corrections/Modifications/Replacement of Questions if any shall be made available to all
students. Take the print out of the Correction File in such cases and distribute to all
students.
--- Content provided by FirstRanker.com ---
(Sd/-)CONTROLLER OF EXAMINATIONS