Download KUHS MBBS First Year 103001 Physiology Paper I Jan 2026 Question Paper

2010 Scheme
Q.P. Code: 103001
Reg. No.: .....................
First Professional MBBS Degree Supplementary Examinations
January 2026

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Physiology - Paper I
Time: 3 Hours
Total Marks: 50
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between
answers ? Indicate the question number correctly for the answer in the margin space

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Answer all parts of a single question together ? Leave sufficient space between answers
Draw table/diagrams/flow charts wherever necessary
Long essay
(10)
1. A 28-year-old woman, a vegetarian, presented with progressive fatigue, numbness

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and tingling in her lower limbs, pallor, shortness of breath on exertion, and
unintentional weight loss over the past two months. She also reported difficulty in
concentrating and mild depression. On clinical examination, she appeared pale with a
mild glossitis. Her blood investigations revealed: RBC count: 2.8 million cells/cu.mm,
Hemoglobin: 6.0 g/dL, MCV: 120 fL, Peripheral smear: hypersegmented neutrophils

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and pancytopenia. After starting parenteral cobalamin therapy, she experienced
marked improvement in energy levels, appetite, and mental clarity, with gradual
weight gain.
a) What is she suffering from.
b) Explain erythropoiesis and which step of erythropoiesis gets affected in her.

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c) Explain the physiological basis behind this blood picture.
d) List the factors regulating erythropoiesis.
(1+5+2+2)
Short essays
(2x5 =10)

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2. Describe the stages of deglutition
3. Explain the conducting system of the heart
Answer briefly
(5x3=15)
4. Isovolumetric relaxation phase

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5. Counter-current multiplier
6. Role of Immunoglobulins in Immunity
7. Chemoreceptors in the regulation of respiration
8. Composition and functions of bile
Draw and label

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(2x2? =5)
9. Lead II ECG
10. Oxygen-Hemoglobin Dissociation Curve
Explain the physiological basis of the following
(5x2=10)

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11. Resting membrane potential in excitable cells
12. Urine concentration in the Distal Convoluted Tubule
13. Heart sounds during the cardiac cycle
14. Increased ventilation at high altitude
15. Cutaneous vasodilation in body temperature regulation

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