RUHS
Second Year MBBS Examination
II MBBS PHARMACOLOGY PAPER II
Time: 3 hours
Max Marks: 100

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Date: 24-12-2022
Instructions: INSTRUCTIONS: Attempt all questions in
both sections: (Use separate answer book for each
section)
Section 1

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1. Fill in the blanks: (6)
a. Ivabradine is indicated in management
of__________
b. Raloxifene is used in the management
of__________

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c. Bivacizumab is used in the treatment of__________
d. Treatment for iron poisoning is__________
e. Drug of choice in paroxysmal supraventricular
tachycardia is__________
f. Drug of choice for cyclophosphamide toxicity

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is__________
2. Multiple choice questions: (4)
a. Gastric lavage is contraindicated in; a) Salicylate
poisoning b) Kerosene poisoning c) OP poisoning d)
Morphine poisoning

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b. The drug obtained from plant digitalis is used for the
treatment of; a) Malaria b) Heart Failure c) MI d)
Iridocyclitis
c. A 30 year old female was treated with an
antihypertensive drug and presented with hirsutism.

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The likely drug was; a) Fenoldopam b) Methydopa c)
Minoxidil d) Enalapril
d. The following drugs cause methemoglobinemia a)
Aniline b) Dapsone c) Nitrates d) All of above
3. A 65 years old male presented in emergency with

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severe pain in chest radiating to jaw and left arm.
ECG showed ST segment elevation and raised
cardiac markers. Diagnosis of acute attack of MI was
made. (15)
a. Write down the management of the above condition.

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b. Discuss the precautions and post Mi prophylaxis for
this patient.
c. Write down the ADR's of Nitrates.
4. Write short notes on (Any five): (10)
a. Management of gestational hypertension

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b. Methotrexate
c. Immunosuppressant
d. Antiplatelet drugs
e. Eplerenone
f. Vitamin K

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5. Explain why (Any three): (15)
a. Furosemide is used in the treatment of acute left
ventricular failure.
b. Levothyroxine T4 is preferred over T3 in
hypothyroidism.

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c. Warfarin has a black box warning on its label.

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d. Metformin is used in polycystic ovarian syndrome.
Section 2
1. A 35 years old female visited medicine department
with complaints of cough, evening rise fever, loss of

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appetite, weight loss since 1 month. After complete
investigations, diagnosis pulmonary Koch's was
made. (20)
a. Mention the drug regimen for this patient
b. Why multi drug therapy is preferred

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c. Write down the side effects of first line drugs
d. Write down the management of XDR tuberculosis
e. Write down the precautions to be taken by the
patient
2. Write short notes on (Any five): (10)

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a. Management of P. falciparum malaria.
b. Management of Urinary tract infections.
c. Amphotericin B.
d. Uses of corticosteroids.
e. Treatment of Psoriasis.

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f. COVID-19 vaccine.
3. Explain Why (Any Four): (20)
a. Penicillins are combined with beta lactam inhibitors.
b. ACE inhibitors are given in patients of CHF.
c. Androgens are used for doping.

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d. Aminoglycosides are used with caution in geriatric
patients.
e. Anticholinergics are contraindicated in glaucoma.

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