RUHS
Second Year MBBS Examination
II MBBS PHARMACOLOGY PAPER II
Date: 02-12-2024
Time: 3 hours
Instructions: INSTRUCTIONS: Attempt all questions in both sections: (Use
separate answer book for each section)
Section 1
1. Fill in the blanks:6x1=06 (6)
is,
b. ________ is used when heparins action needs to be terminated rapidly.
c. Anti thyroid drug preferred in early pregnancy is_______
d. ________ is a thiazolidinedione used in Diabetes Mellitus.
is________
f. __________ is used for radical cure of relapsing plasmodium vivax
malaria.
2. Answer the following (Multiple choice questions):4x1=04 (4)
Chloroquine b) Diloxanide furoate c) Metronidazole d) Dihydroemetine
b. Glycopeptide antibiotic that can cause "Red Man Syndrome' on rapid i.v.
injection is: a) Linezolid b) Clindamycin c) Vancomycin d) Azithromycin
c. Presence of following substance in gastrointestinal tract increases oral iron
d. Preferred diuretic for treatment of mild hypertension is: a)
Hydrochlorothiazide b) Furosemide c) Acetazolamide d) Bumetamide
3. Clinical case study-A 50-year-old male complains of chest pain on exertion
that is relieved on rest. His blood pressure is 130/90 mmHg, rest physical
as classical angina pectoris.
a. Write the drug of choice for acute chest pain in this patient with its
mechanism of action and adverse effects.
b. Enumerate the drugs that can be used for chronic prophylaxis of angina
c. Explain why beta blockers and calcium channel blockers should not be
given in combination.
4. Write short notes on (Any five): 5x2=10 (10)
a. Radioactive lodine
b. Mifepristone
c. Oxytocin
d. Bisphosphonates
e. Angiotensin receptor blockers
f. Amiodarone
a. Insulin analogs
b. Role of aldosterone antagonist in CHF
c. Antiplatelet drugs
d. Oral iron therapy
Section 2
6. Classify Extended Spectrum Penicillins. Describe mechanism of action of
beta lactam antibiotics. Write spectrum, uses and adverse effects of
amoxycillin. 20 (20)
7. Write short notes on (Any five):5 x2=10 (10)
b. TNF a inhibitors
c. Methotrexate
d. Albendazole
e. Fluconazole
8. Explain briefly (Any Four):4x5=20 (10)
a. Drug treatment of Scabies.
b. Artemisinin based combination therapy
c. Post exposure prophylaxis of HIV infection
e. Adverse effects of aminoglycoside antibiotics
***
Second Year MBBS Examination
II MBBS PHARMACOLOGY PAPER II
Date: 02-12-2024
Time: 3 hours
--- Content provided by FirstRanker.com ---
Max Marks: 100Instructions: INSTRUCTIONS: Attempt all questions in both sections: (Use
separate answer book for each section)
Section 1
1. Fill in the blanks:6x1=06 (6)
--- Content provided by FirstRanker.com ---
a. Drug of choice for treatment of Paroxysmal Supraventricular Tachycardiais,
b. ________ is used when heparins action needs to be terminated rapidly.
c. Anti thyroid drug preferred in early pregnancy is_______
d. ________ is a thiazolidinedione used in Diabetes Mellitus.
--- Content provided by FirstRanker.com ---
e. Aminoglycoside antibiotic included in first line drugs for tuberculosisis________
f. __________ is used for radical cure of relapsing plasmodium vivax
malaria.
2. Answer the following (Multiple choice questions):4x1=04 (4)
--- Content provided by FirstRanker.com ---
a. Luminal amoebicide preferred for eradicating cysts in intestine is:a)Chloroquine b) Diloxanide furoate c) Metronidazole d) Dihydroemetine
b. Glycopeptide antibiotic that can cause "Red Man Syndrome' on rapid i.v.
injection is: a) Linezolid b) Clindamycin c) Vancomycin d) Azithromycin
c. Presence of following substance in gastrointestinal tract increases oral iron
--- Content provided by FirstRanker.com ---
absorption: a) Tetracycline b) Phosphates c) Phytates d) Ascorbic Acidd. Preferred diuretic for treatment of mild hypertension is: a)
Hydrochlorothiazide b) Furosemide c) Acetazolamide d) Bumetamide
3. Clinical case study-A 50-year-old male complains of chest pain on exertion
that is relieved on rest. His blood pressure is 130/90 mmHg, rest physical
--- Content provided by FirstRanker.com ---
examination is (15) normal. ECG findings are also normal. He is diagnosedas classical angina pectoris.
a. Write the drug of choice for acute chest pain in this patient with its
mechanism of action and adverse effects.
b. Enumerate the drugs that can be used for chronic prophylaxis of angina
--- Content provided by FirstRanker.com ---
pectoris.c. Explain why beta blockers and calcium channel blockers should not be
given in combination.
4. Write short notes on (Any five): 5x2=10 (10)
a. Radioactive lodine
--- Content provided by FirstRanker.com ---
b. Mifepristone
c. Oxytocin
d. Bisphosphonates
e. Angiotensin receptor blockers
f. Amiodarone
--- Content provided by FirstRanker.com ---
5. Explain briefly (Any three):3 x 5=15 (15)a. Insulin analogs
b. Role of aldosterone antagonist in CHF
c. Antiplatelet drugs
d. Oral iron therapy
--- Content provided by FirstRanker.com ---
Section 2
6. Classify Extended Spectrum Penicillins. Describe mechanism of action of
beta lactam antibiotics. Write spectrum, uses and adverse effects of
amoxycillin. 20 (20)
7. Write short notes on (Any five):5 x2=10 (10)
--- Content provided by FirstRanker.com ---
a. Penicillamineb. TNF a inhibitors
c. Methotrexate
d. Albendazole
e. Fluconazole
--- Content provided by FirstRanker.com ---
f. Treatment of multibacillary leprosy8. Explain briefly (Any Four):4x5=20 (10)
a. Drug treatment of Scabies.
b. Artemisinin based combination therapy
c. Post exposure prophylaxis of HIV infection
--- Content provided by FirstRanker.com ---
d. Newer macrolide antibioticse. Adverse effects of aminoglycoside antibiotics
***