RUHS
Second Year MBBS Examination
II MBBS PHARMACOLOGY PAPER I
Time: 3 hours
Max Marks: 100
Instructions: INSTRUCTIONS: Attempt all questions in both sections:
(Use separate answer book for each section)
Section 1
1. Fill in the blanks: (6)
b. A highly ionized drug is_________________________ by the
kidney.
c. A drug that competes for active binding site is
called_________________________
about_________________________
e. Beta-blocker with peripheral vasodilator action
is_________________________
f. The preferred prophylactic drug for a 34 years old female suffering
2. Answer the followings (Multiple Choice Questions): (4)
a. Which of the following is used in the treatment of Alzheimer's
disease: a) Dronabinol B) Donepezil c) Domperidone d)
Dobutamine
c) Phenytoin d) Sulfasalazine
c. Which of the following drug has highest anticholinergic effect: a)
Fexofenadine b) Cinnarizine c) Promethazine d) Cetrizine
d. Features of opioid intake are all except: a) Feeling of relaxation b)
3. A 24-years-old male presented in emergency n unconscious state.
History reveals frequent episodes of generalized tonic clonic seizures
for last 40 minutes and each (15) episode lasting for 3to 5 minutes.
a. Classify the drugs for epilepsy.
c. Common investigations required for above condition.
d. Write down the adverse drug reactions of phenytoin.
4. Write short notes on (Any five): (10)
a. Drug antagonism.
c. Uses of morphine.
d. Adverse drug reactions of aspirin.
e. Management of Rheumatoid arthiritis.
f. Labetalol.
a. Propranolol is used in prophylaxis of migraine.
b. Pyridostigmine is used in myasthenia gravis.
c. Levodopa is combined with carbidopa.
d. SSRIs are preferred over tricyclic antidepressants in management
Section 2
1. A 62 years old male visited urology department with complaints of
frequent need to urinate, difficulty in initiating stream, and sense of
incomplete voiding. On rectal (20) examination increase in prostate
histopathological examination.
a. Mention the preferred drug for this patient.
b. Write down the mechanism of action of this drug.
c. Write down the most common side effect of this drug.
e. What is the role of finasteride in the treatment of BPH?
2. Write short notes on (Any five): (10)
a. Management of H.pylori infection.
b. Management of organophosphorus poisoning.
d. Management of acute attack of bronchial asthma
e. Prostaglandin analogues.
f. Pre-anesthetic medication.
3. Explain Why (Any four): (20)
b. Ethyl alcohol is used in methyl alcohol poisoning.
c. Adrenaline is used in anaphylactic shock.
d. Oximes not used in carbamate poisoning.
e. Pilocarpine is not preferred first line agent in simple chronic
***
Second Year MBBS Examination
II MBBS PHARMACOLOGY PAPER I
Time: 3 hours
Max Marks: 100
--- Content provided by FirstRanker.com ---
Date: 22-12-2022Instructions: INSTRUCTIONS: Attempt all questions in both sections:
(Use separate answer book for each section)
Section 1
1. Fill in the blanks: (6)
--- Content provided by FirstRanker.com ---
a. Enalapril inhibits the enzyme_________________________b. A highly ionized drug is_________________________ by the
kidney.
c. A drug that competes for active binding site is
called_________________________
--- Content provided by FirstRanker.com ---
d. Phase 4 clinical trials collect information especiallyabout_________________________
e. Beta-blocker with peripheral vasodilator action
is_________________________
f. The preferred prophylactic drug for a 34 years old female suffering
--- Content provided by FirstRanker.com ---
from mania is_________________________2. Answer the followings (Multiple Choice Questions): (4)
a. Which of the following is used in the treatment of Alzheimer's
disease: a) Dronabinol B) Donepezil c) Domperidone d)
Dobutamine
--- Content provided by FirstRanker.com ---
b. Which of the following is not a prodrug: a) Dipivelrine b) Captoprilc) Phenytoin d) Sulfasalazine
c. Which of the following drug has highest anticholinergic effect: a)
Fexofenadine b) Cinnarizine c) Promethazine d) Cetrizine
d. Features of opioid intake are all except: a) Feeling of relaxation b)
--- Content provided by FirstRanker.com ---
Euphoria c) Analgesia d) Dilated pupil3. A 24-years-old male presented in emergency n unconscious state.
History reveals frequent episodes of generalized tonic clonic seizures
for last 40 minutes and each (15) episode lasting for 3to 5 minutes.
a. Classify the drugs for epilepsy.
--- Content provided by FirstRanker.com ---
b. Write down the management of the above condition.c. Common investigations required for above condition.
d. Write down the adverse drug reactions of phenytoin.
4. Write short notes on (Any five): (10)
a. Drug antagonism.
--- Content provided by FirstRanker.com ---
b. Teratogenic drugs.c. Uses of morphine.
d. Adverse drug reactions of aspirin.
e. Management of Rheumatoid arthiritis.
f. Labetalol.
--- Content provided by FirstRanker.com ---
5. Explain briefly (Any three): (15)a. Propranolol is used in prophylaxis of migraine.
b. Pyridostigmine is used in myasthenia gravis.
c. Levodopa is combined with carbidopa.
d. SSRIs are preferred over tricyclic antidepressants in management
--- Content provided by FirstRanker.com ---
of depression.Section 2
1. A 62 years old male visited urology department with complaints of
frequent need to urinate, difficulty in initiating stream, and sense of
incomplete voiding. On rectal (20) examination increase in prostate
--- Content provided by FirstRanker.com ---
size was detected. Benign prostate hypertrophy was confirmed onhistopathological examination.
a. Mention the preferred drug for this patient.
b. Write down the mechanism of action of this drug.
c. Write down the most common side effect of this drug.
--- Content provided by FirstRanker.com ---
d. Name two drugs contraindicated in patients of BPH.e. What is the role of finasteride in the treatment of BPH?
2. Write short notes on (Any five): (10)
a. Management of H.pylori infection.
b. Management of organophosphorus poisoning.
--- Content provided by FirstRanker.com ---
c. Probiotics.d. Management of acute attack of bronchial asthma
e. Prostaglandin analogues.
f. Pre-anesthetic medication.
3. Explain Why (Any four): (20)
--- Content provided by FirstRanker.com ---
a. Sumatripton is preferred over methylergonovine in migraine.b. Ethyl alcohol is used in methyl alcohol poisoning.
c. Adrenaline is used in anaphylactic shock.
d. Oximes not used in carbamate poisoning.
e. Pilocarpine is not preferred first line agent in simple chronic
--- Content provided by FirstRanker.com ---
glaucoma.***