RUHS
Second Year MBBS Examination
II MBBS PHARMACOLOGY PAPER I
Time: 3 hours Max Marks: 100
Date: 07-06-2022
questions in both sections: (Use separate answer
book for each section)
Section 1
1. Fill in the blanks: (6)
Migraine is .........................................................
(. 178, . 333)
b. COMT inhibitor acting on dopamine metabolism
both centrally and
(. 426, . 231)
c. The most common complication of spinal
anaesthesia is
.........................................................(. 369, .
d. Drug of choice for febrile convulsions is
................................................
e. Fastest acting proton pump inhibitor is
....................................................
.....................................................(. 474, .
152)
2. Answer the followings (Multiple Choice Questions):
(4)
effect of the drug b) Allergic effect of the drug c)
Effect seen on chronic use of the drug d) Delayed
effect of the drug
b. Major aim of Phase 1 clinical trial is to know the:
d) Pharmacokinetics
c. Adrenergic beta-receptors having Lipolysis
property in fat cells is: a) Alpha-1 b) Alpha-2 c)
Beta-1 d) Beta-3
include: a) Oral Candidiasis b) Cushing's
syndrome c) Decreased ACH d) Systemic
complications
3. A 48-years-old man visits the ophthalmology OPD
vision. On examination, the intraocular pressure
was 32 mm Hg in (15) right eye and 30 mm Hg in
left cyc. Both iridocorneal angles were open:
a. What is the most probable diagnosis?
Explain its mechanism of action. (A. 87, B. 318)
c. Which other drug can be added if the condition is
not controlled with monotherapy? Explain its
mechanism of action. .(A. 765, B. 739)
do not affect the pupil size.
4. Write short notes on (Any five): (10)
a. Methotrexate in Rheumatoid Arthritis. (A. 862, B.
821)
significance. (A. 31, B. 21)
c. Lithium carbonate. (A. 447, B. 211) (. 34, . 24)
d. Drug tolerance and its types.
e. Treatment of Methyl alcohol poisoning. (A. 110,
f. Uses of Non-Steroidal anti inflammatory drugs.
(A. 629, . 170)
5. Explain briefly (Any three): (15)
a. Why Allopurinol is NOT used in acute gout? (A.
b. Selected serotonin reuptake inhibitors are drug of
choice for depression. (A. 431, B. 229)
c. Dopamine is drug of choice for cardiogenic shock
with oliguria. (A. 524, . 263)
treatment of angina..(A. 142, 143, . 977)
Section 2
1. Enumerate the drugs used in treatment of Grand
Mal Epilepsy. Explain the mechanism of action of
Which drug is (20) preferred if the patient is a
female of 25 years of age and why? Explain the
principle of treatment of Epilepsy.
2. Write short notes on (Any five): (10)
b. Difference between type A and type B adverse
drug reaction.
c. Examples of drugs which can be given by
transdermal drug delivery and mention
d. Most commonly used anti emetic drugs..(A. 136,
B. 268)
e. Antispasmodic anticholinergics.
f. Drug therapy of benign hypertrophy of prostrate.
3. Explain briefly (Any four): (20)
a. Prolonged apnoea by Succinylcholine.
b. Lignocaine - its uses and adverse effects. (A.
361, . 241)
d. Mention any four second generation c and their
uses.
e. Pure opioid antagonists.
***
Second Year MBBS Examination
II MBBS PHARMACOLOGY PAPER I
Time: 3 hours Max Marks: 100
Date: 07-06-2022
--- Content provided by FirstRanker.com ---
Instructions: INSTRUCTIONS: Attempt allquestions in both sections: (Use separate answer
book for each section)
Section 1
1. Fill in the blanks: (6)
--- Content provided by FirstRanker.com ---
a. Drug of choice for aborting acute attack ofMigraine is .........................................................
(. 178, . 333)
b. COMT inhibitor acting on dopamine metabolism
both centrally and
--- Content provided by FirstRanker.com ---
peripherally...........................................................(. 426, . 231)
c. The most common complication of spinal
anaesthesia is
.........................................................(. 369, .
--- Content provided by FirstRanker.com ---
240)d. Drug of choice for febrile convulsions is
................................................
e. Fastest acting proton pump inhibitor is
....................................................
--- Content provided by FirstRanker.com ---
f. Gastric lavage is contraindicated in poisoning of.....................................................(. 474, .
152)
2. Answer the followings (Multiple Choice Questions):
(4)
--- Content provided by FirstRanker.com ---
a. Type B adverse drug reaction is: a) Augmentedeffect of the drug b) Allergic effect of the drug c)
Effect seen on chronic use of the drug d) Delayed
effect of the drug
b. Major aim of Phase 1 clinical trial is to know the:
--- Content provided by FirstRanker.com ---
a) Safety b) Efficacy c) Maximum tolerable dosed) Pharmacokinetics
c. Adrenergic beta-receptors having Lipolysis
property in fat cells is: a) Alpha-1 b) Alpha-2 c)
Beta-1 d) Beta-3
--- Content provided by FirstRanker.com ---
d. Common complication of aerosol steroidsinclude: a) Oral Candidiasis b) Cushing's
syndrome c) Decreased ACH d) Systemic
complications
3. A 48-years-old man visits the ophthalmology OPD
--- Content provided by FirstRanker.com ---
with history of gradual painless partial loss ofvision. On examination, the intraocular pressure
was 32 mm Hg in (15) right eye and 30 mm Hg in
left cyc. Both iridocorneal angles were open:
a. What is the most probable diagnosis?
--- Content provided by FirstRanker.com ---
b. What is the drug of choice for this condition?Explain its mechanism of action. (A. 87, B. 318)
c. Which other drug can be added if the condition is
not controlled with monotherapy? Explain its
mechanism of action. .(A. 765, B. 739)
--- Content provided by FirstRanker.com ---
d. Name two drugs used in the given condition thatdo not affect the pupil size.
4. Write short notes on (Any five): (10)
a. Methotrexate in Rheumatoid Arthritis. (A. 862, B.
821)
--- Content provided by FirstRanker.com ---
b. Plasma protein binding and its clinicalsignificance. (A. 31, B. 21)
c. Lithium carbonate. (A. 447, B. 211) (. 34, . 24)
d. Drug tolerance and its types.
e. Treatment of Methyl alcohol poisoning. (A. 110,
--- Content provided by FirstRanker.com ---
B. 289)f. Uses of Non-Steroidal anti inflammatory drugs.
(A. 629, . 170)
5. Explain briefly (Any three): (15)
a. Why Allopurinol is NOT used in acute gout? (A.
--- Content provided by FirstRanker.com ---
216, . 1036)b. Selected serotonin reuptake inhibitors are drug of
choice for depression. (A. 431, B. 229)
c. Dopamine is drug of choice for cardiogenic shock
with oliguria. (A. 524, . 263)
--- Content provided by FirstRanker.com ---
d. Cardioselective beta blockers are preferred intreatment of angina..(A. 142, 143, . 977)
Section 2
1. Enumerate the drugs used in treatment of Grand
Mal Epilepsy. Explain the mechanism of action of
--- Content provided by FirstRanker.com ---
the drugs with the help of a labelled diagram.Which drug is (20) preferred if the patient is a
female of 25 years of age and why? Explain the
principle of treatment of Epilepsy.
2. Write short notes on (Any five): (10)
--- Content provided by FirstRanker.com ---
a. Bronchodilators in asthma. (A. 233, . 364)b. Difference between type A and type B adverse
drug reaction.
c. Examples of drugs which can be given by
transdermal drug delivery and mention
--- Content provided by FirstRanker.com ---
advantages of this route. (A. 6, . 8)d. Most commonly used anti emetic drugs..(A. 136,
B. 268)
e. Antispasmodic anticholinergics.
f. Drug therapy of benign hypertrophy of prostrate.
--- Content provided by FirstRanker.com ---
977)3. Explain briefly (Any four): (20)
a. Prolonged apnoea by Succinylcholine.
b. Lignocaine - its uses and adverse effects. (A.
361, . 241)
--- Content provided by FirstRanker.com ---
c. Proton pump inhibitors. (A. 429, . 228)d. Mention any four second generation c and their
uses.
e. Pure opioid antagonists.
***
--- Content provided by FirstRanker.com ---