The West Bengal University of Health Sciences
MBBS 1st Professional Examination, January 2020
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Subject: Biochemistry
Paper : II
Full Marks: 50
Time: 2 ½ hours
Attempt all questions. The figures in the margin indicate full marks.
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Group A
- a) i) With the help of a suitable diagram explain the "Lac- operon model" of regulation of gene expression in bacteria. 10+2
ii) Differentiate between the mono- cistronic & poly- cistronic m- RNA.
or
b) i) Name the different types of DNA damage. 2+2+8--- Content provided by FirstRanker.com ---
ii) Mention different types of DNA repair.
iii) With the help of diagram differentiate between 'Mismatch repair' & 'Base excision repair'.
Group B
- Answer any two of the following:
a) Write down the oxidative phase of HMP shunt pathway & its importance. 6+1--- Content provided by FirstRanker.com ---
b) Name ketone bodies. Outline the steps of synthesis & utilization of ketone bodies. 1+6
c) Outline the process of synthesis of ammonia in human system. State different routes of disposal of ammonia from human body. 4+3
Group C
- Write short note on any four of the following: 4 x 3
a) Phase II reaction of Xenobiotics.--- Content provided by FirstRanker.com ---
b) Insulin receptor.
c) Phenyl ketonuria.
d) Transmethylation.
e) Genetic code.
Group D
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- Explain the following statement: 4 x 3
a) Atorvastatin lowers the serum cholesterol level in hypercholesterolemic individuals.
b) Normal function of the kidney is essential for the synthesis of active Vitamin D3.
c) P53 is considered as "Guardian of the genome".
d) Ascorbic acid helps in the maturation of the immature collagen molecule.
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This download link is referred from the post: MBBS WBUHS Last 17 Years (2008-2025) First Year Question Papers (The West Bengal University of Health Sciences)
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