Download WBUHS MBBS 1st Year WBUHS Physiology Paper I 2022 June Question Paper

The West Bengal University of Health Sciences

MBBS 1^st Professional Examination (New Regulation), June, 2022

--- Content provided by FirstRanker.com ---

Subject: Physiology

Paper: I

Attempt all questions. The figures in the margin indicate full marks.

Full Marks: 100

Time: 3 hours

--- Content provided by⁠ FirstRanker.com ---

1. A 20 year male was brought to the emergency department following a road traffic accident with history of blood loss. On examination there is tachycardia, BP 60/40 mm of Hg. What is the type of shock the patient is suffering from? Enumerate the different types of shock. Describe the stages of shock. If you need to transfuse blood to this patient what are the precautions that you need to take and what are the investigations you need to conduct ? What are the homeostatic mechanisms that will come into play as life saving measures for this patient ? (1+2+2+3+4+3)
2. With a labeled diagram show the different secretory glands of stomach. Enumerate their different secretions. Describe the mechanism of gastric acid secretion. How is the stomach itself gets protected from corrosive effect of gastric acid? (4+4+4+3)
3. 1. What are the different types of chemoreceptors regulating ventilation? How are they stimulated? List the pathways by which increased PCO₂ stimulates ventilation.
   2. What is active transport? Discuss secondary active transport with examples. Describe the mechanism of exocytosis.
   3. Define cardiac output. What are the factors regulating cardiac output? What are the methods you know which can be utilized to measure cardiac output? Briefly describe one method to measure cardiac output. (2+3+2+3)

   --- Content provided by‌ FirstRanker.com ---

4. Write a short note on the following: (2x5)
   1. Attitude of a doctor towards AIDS patients.
   2. Myasthenia Gravis.
5. Explain the following statements: (5x4)
   1. Hematocrit of the venous blood is more than that of arterial blood.

   --- Content provided by‍ FirstRanker.com ---

   2. Low dose Aspirin is prescribed in patients with coronary thrombosis.
   3. Jaundice is produced when a person has a high rate of RBC destruction.
   4. Residual volume in the lung is essential for smooth breathing.
   5. Gastric pH is auto-regulated.

--- Content provided by‌ FirstRanker.com ---

6. Choose the correct option in each of the following: (10x1)
   1. Stokes Adams syndrome occurs in :
      1. First degree heart block.
      2. Systemic hypertension.
      3. Wenckebach phenomenon.
      4. Complete heart block.

   --- Content provided by‍ FirstRanker.com ---

   2. Macrophages are the mature forms of
      1. Neutrophils.
      2. Basophils.
      3. Monocytes.
      4. Lymphocytes.

   --- Content provided by‌ FirstRanker.com ---

   3. J receptors are present in:
      1. Walls of the alveoli.
      2. Walls of trachea.
      3. Pulmonary capillary wall.
      4. Pulmonary interstitium.

   --- Content provided by⁠ FirstRanker.com ---

   4. Hypokalemia causes:
      1. Increased amplitude of action potential.
      2. Hyperpolarisation.
      3. Resting membrane potential becomes less negative
      4. Tetany

   --- Content provided by FirstRanker.com ---

   5. All are secreted as proenzymes except:
      1. Trypsin.
      2. Chymotrypsin.
      3. Pepsin.
      4. Ribonuclease.

   --- Content provided by FirstRanker.com ---

   6. Patients with human immuno-deficiency virus (HIV) exhibit abnormal functioning of which of the following mechanisms.
      1. Antibody production only.
      2. T cell-mediated cytoxicity only.
      3. Degranulation of appropriately stimulated mast cells.
      4. Both antibody production and T cell mediated cytotoxicity.

   --- Content provided by‍ FirstRanker.com ---

   7. Resting membrane potential of myelinated nerve fibre is primarily dependent on concentration of:
      1. Potassium ion.
      2. Sodium ion.
      3. Chloride ion.
      4. Bicarbonate ion.

   --- Content provided by‍ FirstRanker.com ---

   8. Pulmonary compliance depends on all except:
      1. Alveolar diameter.
      2. Surfactant.
      3. State of the interstitium.
      4. Amount of capillary blood.

   --- Content provided by​ FirstRanker.com ---

   9. The average end diastolic volume is:
      1. 60-80ml.
      2. 120-130ml.
      3. 180-200ml.
      4. 40-60ml.

   --- Content provided by FirstRanker.com ---

   10. 1 gram of haemoglobin carries :
       1. 1.84ml O₂.
       2. 2.62ml O₂.
       3. 1.34ml O₂.
       4. 2.6ml O₂.

   --- Content provided by‍ FirstRanker.com ---

P.T.O

www.FirstRanker.com