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02/22
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The West Bengal University of Health Sciences
MBBS 2nd Professional Examination (Old Regulation) September 2022
Subject: Pharmacology
Paper: II
Full Marks: 40
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Time: 2 hours
Attempt all questions. The figures in the margin indicate full marks.
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- Enumerate antithyroid drugs. What is the mechanism of action of iodine as antithyroid agent? How will you manage a case of myxedema coma.
Or
3+4+3 - Enumerate glucocorticoids. Describe the therapeutic uses and adverse effects of glucocorticoids. Explain why glucocorticoids should not be withdrawn abruptly after prolonged therapy.
3+3+2+2
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- Enumerate antithyroid drugs. What is the mechanism of action of iodine as antithyroid agent? How will you manage a case of myxedema coma.
- Explain any three of the following:
- Tetracyclines are contraindicated in pregnancy.
- Morphine is contraindicated in undiagnosed abdominal pain.
- Both estrogen and progesterone are combined in oral contraceptive pill.
- Centrally acting anticholinergics are used in drug induced parkinsonism.
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- Write the mechanism of action of any three of the following:
- Lactulose in hepatic encephalopathy.
- Lithium in bipolar disorder.
- Multi drug therapy is used in the treatment of tuberculosis.
- Metformin as oral antidiabetic agent.
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- Write short notes on any four of the following:
- Amphotericin B.
- Ketamine.
- Metronidazole.
- Post exposure prophylaxis against HIV.
- Methotrexate.
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