Download MBBS 2nd Year WBUHS Pharmacology Paper II 2010 Question Paper

PHARMACOLOGY

Paper - II

Use Seperate answer script for each group

2010Full Marks 40

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Attempt all questions. The figures in the margine indicate distribution of marks in each questions

Group - A

1. (a) Enumerate drugs acting via benzodiazepine-GABA-A receptor complex channel. Discuss the therapeutic uses of benzodiazepines and the treatment of its overdosage. 4+4+2

Or (b) Enumerate drugs used for chloroquine resistant P. falciparum malaria. Describe drug treatment of uncomplicated falciparum malaria mentioning the dosage regimes and important adverse effects of drugs used. 2+5+3

Group - B

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2. Explain why (any three) : 3 x 3

a) Cisapride has been withdrawn in some countries.

b) Long-term use of glucocorticoids is potentially hazardous.

c) Propofol is a popular i.v. Anaesthetic agents.

d) Azithromycin is considered superior to erythromycin.

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Group - C

3. Discuss the mechanism of action of (any three) : 3 x 3

a)Combined oral contraceptive steroids

b) Acyclovir in the treatment of herpes viral infection.

c) Ondansetron as antiemetic agent.

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d) Indomethacin for treatment of patent ductus arteriosus.

Group -D

4. Write short notes on (any four) : 4 x 3

a) Sodium valproate

b) dioactive iodine

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c) Levodopa

d) Bisphosphonates

e) Therapeutic uses of fluroquinolon