[Max. Marks: 100]
PAPER II: PHARMACOGENOMICS
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Q.P. CODE: 9695
Your answers should be specific to the questions asked.
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Draw neat, labeled diagrams wherever necessary.LONG ESSAY
2 X 20 = 40 Marks
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1.
Write a note on Human Genome Variation. Explain Positional Cloning and Gene Mapping.
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2.Effect of SNPs on Drug responses
SHORT ESSAY
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5 X 10 = 50 Marks
3.
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Explain the difference between Proteomics and Metabonomics.4.
Write different phases of Drug metabolism.
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5.
Give an account of types of Receptors.
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6.Write the importance of Pharmacogenomics of Personalized Medicines.
7.
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Pharmacogenetics of Cardiac Ion Channels
SHORT NOTES
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2 X 5 =10 Marks8.
Haplotypes
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9.
Microarray
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