Approach for a patient with Jaundice
History (focus on medication/drug exposure)
Physical examination
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Lab Tests: Bilirubin with fractionation, ALT, AST, ALP, PT and Albumin
| Isolated elevation of the bilirubin | Bilirubin and other LFTs Also deranged | |
| Direct Hyperbilirubinemia (Direct > 15%) Inherited Disorders: --- Content provided by FirstRanker.com --- Dubin Johnson Syndrome Rotor's Syndrome Indirect Hyperbilirubinemia (Direct <15%) Drugs: Rifampicin --- Content provided by FirstRanker.com --- Probenecid Inherited disorders: Gilbert's Syndrome Criggler Najjer Syndrome Hemolytic disorders --- Content provided by FirstRanker.com --- Ineffective erythropoiesis | Hepatocellular Pattern: ALT/AST elevated out of proportion to ALP
--- Content provided by FirstRanker.com --- Additional virologic testing CMV DNA, EBV capsid antigen, Hepatitis D antibody, Hepatitis E IgM --- Content provided by FirstRanker.com --- Liver Biopsy | Cholestatic pattern: ALP out of proportion to AST/ALP Ultrasound Dilated ducts Extrahepatic Cholestasis --- Content provided by FirstRanker.com --- CT/ERCP Ducts Not Dilated Intrahepatic Cholestasis Serologic Testing AMA --- Content provided by FirstRanker.com --- Hepatitis Serologies Hepatitis A, CMV, EBV MRCP/Liver Biopsy Liver Biopsy |
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This download link is referred from the post: MBBS 2021 Important Topics and Materials for 1st Year, 2nd Year, 3rd Year and Final Year
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