Potassium Permanganate Lotion
Object - to prepare and dispense 50ml of potassium permanganate lotion.
Calculation -
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- Calculate the amount of potassium permanganate required.
1:5000 Ratio means - 1gm of potassium permanganate in 5000ml water
1000 mg potassium permanganate in 5000ml solution
50ml solution - 10 mg potassium - Calculate the amount of stock solution required.
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1% KMnO4 (1gm KMnO4 in 100ml of solution)
10mg KMnO4 is present in 1ml of stock solution
Method -
Prepare stock solution by dissolving 100mg of KMnO4 in 100ml of water in a glass mortar. Then take 1ml solution and add water up to 50ml. Transfer it to dispensing bottle, put cork and label it.
Indication
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- 1:100 Solution is used in mycotic infection such as athlete's foot.
- 1:200 Solution for stomach wash in morphine and phosphorus poisoning.
- 1:1000 to 1:4000 Solution is used as a clinging application for sterilization of instruments.
- 1:5000 to 1:10,000 Solution is used as eye wash, mouth wash, stomach wash in case of alkaloid poisoning, wet dressing, as an antiseptic in urethral and vaginal infection.
- Direct crystals are topically applied in snake bite at the site of bite.
- Used as styptic 5% (1:20) to prevent local bleeding.
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Precautions -
- Lotions are dispensed in light resistant bottles, photosensitive.
- For external use only.
Disadvantage -
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- It causes rusting, thus not suitable for disinfecting instruments.
- At higher concentration, it stains the skin and clothes. May cause burn or blister on skin.
- Activity is reduced in presence of organic matter and oral ingestion cause gastric irritation, renal and coma.
Prescription
Dinesh 16 years Male
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Dr. Ramgopal MBBS 1554406 Trivani Nagar, Jaipur
Diagnosis - ulcer
R Potassium permanganate-10mg Aqua ad 50 ml
Mft - Lotio send such 50ml.
Signa - wash the ulcer two to three times daily, for external use only.
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Label
50ML OF 1:5000
POTASSIUM PERMANGANATE LOTION
FOR EXTERNAL USE ONLY
Dinesh 16 years Male
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Direction - wash ulcer 2-3 times a day.
Pharmacy Lab SMSMC Jaipur
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