PAPER CODE: MB2019102
KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE - 506007
First Year M.B.B.S. (NEW REGULATION) DEGREE EXAMINATION: MARCH 2021
BIOCHEMISTRY PAPER-II
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Time: 3 Hours
Max Marks: 100
Note: Answer all questions.
Give Diagrammatic representation wherever necessary.
Long Answer Questions 2X15=30
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- A new born baby develops yellowish discolouration of skin and conjunctiva after 3 days of birth. The condition is handled by giving phototherapy
- What type of jaundice is it?
- Name the biochemical test for its diagnosis?
- Describe heme is degraded in the body.
- Write about transport, conjugation, secreation and excreation of bilirubin
- What is jaundice? Describe the different types of Jaundice and their causes
- What is the normal serum bilirubin level.
- Significance of entero hepatic circulation. (1+1+3+4+3+1+2)
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- Discuss the metabolism of glycine? Give an account on biologically important compounds synthesised from glycine. Add a note on primary hyperoxaluria. (6+7+2)
Short Answer Questions: 8X5=40
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- Lesch-nyhan syndrome.
- Give an account on DNA repair mechanisms.
- Give an account on transcription? Add a note on inhibitors of transcription
- Write about biologically important peptides.
- Describe Urea cycle.
- What are tumor markers? Discuss the clinical utility of any three tumor markers.
- What is glomerular filtration rate(GFR)? Name the renal clearance tests. Give details of creatinine clearance test.
- Hyperthyroidism
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Very Short Answer Questions: 10X3=30
- Structural organization of proteins.
- Orotic aciduria
- Give an account on mutations.
- Clinical applications of PCR
- Write about metabolic acidosis.
- Hormonal regulation of calcium level
- Normal Serum reference ranges of NPN substances,
- S-Adenosyl Methionine.
- Clinical applications of electrophoresis.
- Phenylketonuria.
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