Download RUHS 2nd Year MBBS Pathology Paper II 2022 December Question Paper

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28-12-2022 01221 A3+01221 A4

II-MBBS Second M.B.B.S. (Main) Examination (New Scheme)

December - 2022

PATHOLOGY

Paper-Second

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Time: Three Hours

Maximum Marks: 100

Attempt all questions in both sections

(Use separate answer book for each section)

Section-A

1. Fill in the blanks: 6 x 1 = 06
   1. Earliest light microscopic change in myocardial infarction __________

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   2. Definite diagnosis of Barrett's esophagus requires __________ cells.
   3. Ulcers in duodenum associated with burns are __________ ulcers.
   4. Gleason's scoring is used in __________ carcinoma.
   5. Luminal A tumours of carcinoma breast are ER positive and __________ negative.
   6. Capsular & vascular invasion is criteria for malignancy in __________ carcinoma of thyroid.

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2. Answer the followings (Multiple Choice Questions): 4 x 1 = 04
   1. Following is most commonly associated with lung cancer
      1. Asbestosis
      2. Silicosis
      3. Berylliosis
      4. Coal workers pneumoconiosis

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   2. Minimum number of red blood cells per hpf of urine required for diagnosis of hematuria is
      1. 3
      2. 5
      3. 8
      4. 10

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   3. Microalbumiuria is defined as protein levels of
      1. 100-150 mg/d
      2. 151-200 mg/d
      3. 30-300 mg/d
      4. 301-600 mg/d

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   4. IgM antiHBc is
      1. Marker of window period
      2. Seen in chronic infection
      3. Seen in vaccinated person
      4. Denotes high infectivity

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3. A 5 year old male child was brought to OPD with parents noticing increasing lethargy & anorexia over past 2 weeks. On examination - puffiness around eyes & lower extremities showing pitting edema. Temperature & blood pressure normal. Lab findings - urine protein 4+ no dysmorphic RBC. Patient responded well to steroids.
   1. What is your probable diagnosis? 01
   2. Enumerate common causes. 02

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3. Describe the etiopathogenesis of the disease. 05
4. What are its complications? 05
5. Write short notes on (Any five): 5 x 2 = 10
   1. Dystrophic calcification

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   2. Difference between red & white infarct
   3. X linked recessive disorders
   4. Mode of spread of malignant tumours
   5. Causes of Eosinophilia
   6. Difference between lymphoblast and myeloblast

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6. Explain briefly (Any three): 3 x 5 = 15
   1. Type IV hypersensitivity reaction
   2. Peripheral blood smear features of iron deficiency anaemia
   3. Chronic lymphocytic leukaemia
   4. Cardiogenic shock

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Section-B

6. Define anaemia. Tabulate its morphologic classification. Describe the peripheral blood smear findings and red cell indices in megaloblastic anaemia. 20
7. Write short notes on (Any five): 5 x 2 = 10
   1. Causes of microcytic hypochromic anaemia
   2. Vitamin A deficiency
   3. Virchow triad

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   4. Trisomy 21
   5. Alfa fetoprotein
   6. Metaplasia
8. Write briefly about (Any four): 4 x 5 = 20
   1. Hemoglobin estimation techniques

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   2. ESR
   3. Hemophilia A
   4. Reactive systemic amyloidosis
   5. Peripheral blood smear findings of chronic myeloid leukemia

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