Download RUHS 2nd Year MBBS Pharmacology Paper I 2022 December Question Paper

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(This paper consists of 2 pages)

01211 A1+01211 A2

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22-12-2022

II-MBBS

Second M.B.B.S. (Main) Examination (New Scheme)

December - 2022

PHARMACOLOGY

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Paper-First

Time: Three Hours

Maximum Marks: 100

Attempt all questions in both sections

(Use separate answer book for each section)

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Section-A

1. Fill in the blanks: 6 x 1 = 06
   1. Enalapril inhibits the enzyme _______________.
   2. A highly ionized drug is _______________ by the kidney.
   3. A drug that competes for active binding site is called _______________.
   4. Phase 4 clinical trials collect information especially about _______________.
   5. Beta-blocker with peripheral vasodilator action is _______________.

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   6. The preferred prophylactic drug for a 34 years old female suffering from mania is _______________.
2. Answer the followings (Multiple Choice Questions): 4 x 1 = 04
   1. Which of the following is used in the treatment of alzheimer's disease:
      1. Dronabinol
      2. Donepezil
      3. Domperidone

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      4. Dobutamine
   2. Which of the following is not a prodrug:
      1. Dipivefrine
      2. Captopril
      3. Phenytoin

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      4. Sulfasalazine
   3. Which of the following drug has highest anticholinergic effect:
      1. Fexofenadine
      2. Cinnarizine
      3. Promethazine

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      4. Cetrizine
   4. Features of opioid intake are all except:
      1. Feeling of relaxation
      2. Euphoria
      3. Analgesia

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      4. Dilated pupil
3. A 24-years-old male presented in emergency in unconscious state. History reveals frequent episodes of generalized tonic clonic seizures for last 40 minutes and each episode lasting for 3 to 5 minutes.
   1. Classify the drugs for epilepsy. 05
   2. Write down the management of the above condition. 05

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   3. Common investigations required for above condition. 02
   4. Write down the adverse drug reactions of phenytoin. 03
4. Write short notes on (Any five): 5 x 2 = 10
   1. Drug antagonism.
   2. Teratogenic drugs.

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Section-B

5. 1. Nagler's reaction.
   2. Zoster/ Shingles.
   3. Amoebic liver abscess.

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   4. Enumerate Pneumococcal vaccines.
   5. Antigenic shift.
   6. Non suppurative manifestations of Streptococcus pyogenes.
6. Explain briefly (Any three): 3 x 5 = 15
   1. Neurocysticercosis.

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   2. Lab diagnosis of anthrax.
   3. Dermatophytes.
   4. Lab diagnosis of syphilis.
7. Enumerate causative agents of urinary tract infection. Write predisposing factors, pathogenesis, clinical features and Lab diagnosis of UTI. 20

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8. Explain briefly (Any five): 5 x 2 = 10
   1. Post exposure prophylaxis of rabies.
   2. Giardiasis.
   3. Staphylococcal scalded skin syndrome.
   4. Pathogenesis of tetanus.
   5. Enumerate agents of interstitial pneumonia/atypical pneumonia.

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   6. Classify Non Tubercular Mycobacteria with examples.
9. Explain briefly (Any four): 4 x 5 = 20
   1. Lab diagnosis of tuberculosis infection.
   2. Pathogenesis of poliomyelitis.
   3. Lab diagnosis of Diphtheria.

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   4. Lab diagnosis of Hepatitis B.
   5. Lab diagnosis of Pyogenic meningitis.

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