Paper-II
(New Course)
Time Allowed : 3 Hours Maximum Marks : 100
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Illustrate Your answers with suitable diagrams wherever required.
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SECTION-A
(Multiple Choice Questions) (20×1=20)
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Unilateral contracted smooth kidney is seen in
- Reflux nephropathy.
- Lobar infarction
- Renal artery stenosis
- Chronic glomerulonephritis
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Northern Blot test is used for
- DNA analysis
- RNA analysis
- Analysis of proteins
- Enzyme analysis
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(2)MB-II/12(R)-234101
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Most commonly used Fixative in Histopathology is
- Ethyl alcohol
- Buffered Neutral 10% formalin
- Glutaraldehyde
- Bouin's solution
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Amniocentesis to detect chromosomal abnormalities can be done as early as.
- 14th week of gestation
- 18th week of gestation
- 22nd week of gestation
- 26th week of gestation
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A 55 years old female presents with tinnitus, dizziness and history of progressive deafness. Differential diagnosis includes all except.
- Acoustic neuroma
- Endolymphatic hydrops
- Meningioma
- Histiocytosis
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(3) MB-II/12(R)-234101
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Which of the following usually produce osteoblastic secondaries?
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- Carcinoma lung
- Carcinoma breast
- Carcinoma urinary bladder
- Carcinoma prostatic
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Marker for Rhabdomyosarcoma is
- Desmin
- Synaptophysin
- Keratin
- Inhibin
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Primary cause of oedema in nephritic syndrome is
- Na and H₂O retention
- Increased venous pressure
- Protein loss
- Hyperlipidemia
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Microalbuminuria is defined as
- 0.3-0.5 gm of 24 hrs urinary protein
- <0.03 gm of 24 hrs protein
- 0.03-0.3 gm of 24 hrs urinary protein
- >2.5 gm 24 hrs urine proteins
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(4) MB-II/12(R)-234101
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Sample for blood glucose estimation while sending it from collection centre laboratory should be preserved in
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- Sodium Flouride
- Citrate
- EDTA
- Heparin
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Cytological examination of pleural effusion in a 60 years old man revealed the presence of malignant cells. The most likely primary tumor will be.
- Lymphoma
- Cancer breast
- Cancer colon
- Lung cancer
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The tissue of origin of Kaposi's sarcoma is
- Lymphoid
- Vascular
- Neural
- Muscular
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Which of the following is known as guardian of the genome?
- P53
- B mdm2
- CP 14
- AIN
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(5) MB-II/12(R)-234101
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Michaelis Gutmann Bodies are seen in
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- Xanthogranulomatous pyelonephritis
- Malakoplakia
- Nail patella syndrome
- Urinary bladder tumour
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Protein product of HPV 16 is:
- E2
- E5
- E6
- E7
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Which of the following are predominant cells in 48 hrs old infarct.
- Neutrophils
- Plasma cells
- Histiocytes
- Fibroblasts
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Targeted therapy against which of the following targets is used in treatment of lung cancer.
- BRAF
- PIK3CA
- EGFR
- Bel2
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(6) MB-II/12(R)-234101
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Linitis plastica is a form of
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- Gastric carcinoma
- Chronic atrophic gastritis
- Peptic ulcers
- Achalasia cardia
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Bilirubin in urine will be found in which of the following condition
- Criggler-Najjar syndrome
- Gilbert's syndrome
- Dubin Johnson Syndrome
- Sickle Cell Disease
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Higher incidence of lymphoma is seen in the following condition.
- Grave's disease
- Hashimoto's thyroiditis
- Nodular goiter
- Reidel's thyroiditis
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SECTION-B
(Very short Answers) (5×2=10)
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Enumerate gross features of Bronchiectasis.
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Enumerate lesions of Diabetic Nephropathy
(7) MB-II/12(R)-234101
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Name two methods of diagnosis of Helicobacter pylori.
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What is triple negative breast cancer.
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Name one special stain and one IHC marker to confirm presence of melanin pigment.
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SECTION-C
(Short Answers) (10×3=30)
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Give classification of Salivary gland tumors.
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Write short notes on Retinoblastoma.
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Give contrasting features of lobar pneumonia and bronchopneumonia.
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Differentiate between Crohn's Disease and Ulcerative colitis.
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Short note on serological markers in case of viral hepatitis.
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Give salient features of Chronic Pyelonephritis.
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Write WHO classification of testicular tumors (2016).
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Briefly describe Fibroadenoma Breast.
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What is Pheochromocytoma.
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Elaborate on Osteosarcoma.
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(8) MB-II/12(R)-234101
SECTION-D
(Long Answers) (5×8=40)
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- Discuss pathogenesis and pathology of Atherosclerosis.
- Give contrasting features of Transmural and subendocardial infarct.
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- Give an account of Asbestos related disease in humans.
- Differentiate between Tubercular and Typhoid ulcers of small intestine.
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- Briefly discuss Liver function tests.
- Describe Polycystic kidney disease.
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- Discuss Carcinoma Prostate with special reference to Gleason's Grading system.
- Describe Leiomyomas and Adenomyosis.
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- Describe lesions of Diabetic Retinopathy.
- Give CSF findings in different types of meningitis.
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