Download KUHS MBBS 1st Year 2021 March 2019 Scheme 115001 Biochemistry Paper I Question Paper

Download Kerala University of Health Sciences (KUHS) MBBS (Bachelor of Medicine and Bachelor of Surgery) 1st Year (First Year) 2021 March 2019 Scheme 115001 Biochemistry Paper I Previous Question Paper

2019 Scheme
Q.P. Code: 115001
Reg. no.: .....................
First Professional MBBS Degree Regular Examinations March 2021
Biochemistry - Paper I
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers ?
Indicate the question number correctly for the answer in the margin space ? Answer all parts of a single
question together
Leave sufficient space between answers ? Draw table/diagrams/flow charts wherever necessary

Long Essays
(2x15=30)
1. 23-year-old female was brought to casualty with the complaints of dizziness, weakness
and fainting attack. History revealed that she had skipped her breakfast and lunch with
intention of losing weight. Random blood glucose was 40 mg/dl. All other investigations
were normal.
What is the probable diagnosis
What is the normal blood glucose level
Describe the regulation of blood glucose.
Add a note on glucose tolerance test.
(1+1+8+5)
2. Define enzyme. Classify with suitable examples. Discuss the various types of enzyme
Inhibitions with clinical examples.
(1+5+9)
Short essays
(5x8=40)
3. Molecular basis, clinical features and diagnosis of sickle cell anemia.
(2+4+2)
4. Outline the metabolism of glycine under following heads.
Synthesis of glycine, synthesis of biologically important compounds from glycine. (2+6)
5. Describe the steps of beta oxidation. Calculate the energetics from palmitic acid. (6+2)
6. Causes, clinical features, biochemical manifestations and treatment of kwashiorkor.
(2+2+2+2)
7. Sources, biochemical functions and deficiency manifestations of niacin.
(2+4+2)
Short answers
(5x4=20)
8. Inhibitors of electron transport chain.
9. Fat is burnt under the fire of carbohydrates. Justify this statement.
10. Galactosemia.
11. Isoenzymes and their clinical significance
12. Endoplasmic reticulum.
Give Precise Answers
(10x1=10)
13. Protein digestion starts in-----------
14. Primary structure of a protein refers to-----------
15. Curd is an effective treatment for or lactose intolerance. Justify.
16. Name two clinical conditions costing ketosis.
17. Two examples for uncouples of electron transport chain.
18. Patients with G6PD deficiency should not be treated with anti-malarials. Why.
19. Normal serum cholesterol level
20. Enzyme defect in Gaucher's disease.
21. Name the aromatic amino acids
22. Name the essential fatty acids.
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