Download KUHS MBBS 1st Year 2021 March 2019 Scheme 116001 Biochemistry Paper II Question Paper

Download Kerala University of Health Sciences (KUHS) MBBS (Bachelor of Medicine and Bachelor of Surgery) 1st Year (First Year) 2021 March 2019 Scheme 116001 Biochemistry Paper II Previous Question Paper

2019 Scheme
Q.P. Code: 116001
Reg. no.: .....................
First Professional MBBS Degree Regular Examinations March 2021
Biochemistry - Paper II
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers ?
Indicate the question number correctly for the answer in the margin space
Answer all parts of a single question together ? Leave sufficient space between answers
Draw table/diagrams/flow charts wherever necessary
Long Essays
(2x15=30)
1. A 20 years old young man was bought to casualty with road traffic accident. He
sustained injury to chest wall. ABG analysis showed pH 7.25, pCo2 54 mm Hg, HCo3
is 23 mEq/L.
Explain the mechanism of maintaining Blood pH.
What is the diagnosis
What is the biochemical change in these disorders
Define the other acid base balance disorders
(7+2+3+3)
2. ? Define transcription.
? Steps of transcription in prokaryotes.
? Post transcriptional modification.
? Inhibitors of transcription.
(1+8+3+3)
Short essays
(5x8=40)
3. Steps and applications of polymerized chain reaction.
4. Antioxidants: definition and classification.
(8)
5. Explain source, RDA, absorption, transport and shortage of Iron.
6. Principles and application of electrophoresis.
(2+6)
7. What are different types and function of Immunoglobulin.
Short answers
(5x4=20)
8. Name four tumour markers and its significance.
9. Elastin.
10. Explain the Genetic code. What are the salient features of genetic code.
11. Explain detoxification. Explain different phase of detoxification.
12. A/G ratio.
Give Precise Answers
(10x1=10)
13. eGFR.
14. Creatine kinase.
15. Name two vectors of gene therapy.
16. Mutagens.
17. Henderson Hasselbach equation.
18. Functions of fluoride.
19. Lesh Nyhan syndrome.
20. Normal serum potassium and sodium.
21. Name three hormones regulating blood calcium level.
22. Two causes of metabolic alkalosis.
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