Download RGUHS B.Pharm 2020 4th Year-Final Year 2619 Medicinal Chemistry II Revised Scheme 3 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) Bachelor of Pharmacy (B.Pharm) 2020 4th Year-Final Year 2619 Medicinal Chemistry II Revised Scheme 3 Previous Question Paper

Rajiv Gandhi University of Health Sciences
IV Year B.Pharm Degree Examination - 20-Jan-2020
Time: 3 Hours
[Max. marks : 70]

Medicinal Chemistry II
(Revised Scheme ? 3)
QP Code: 2619
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
LONG ESSAY (Answer any two)
2 X 10 = 20 Marks
1. Classify diuretics with examples. Give the mechanism of action of loop diuretics. Write the synthesis
of ethacrynic acid and furosemide.
2. Classify antimalarials with example. Give their mechanism of action. Write synthesis of
trimethoprim and pamaquine.
3. Classify local anti infective agents with examples. Explain the synthesis of Furazolidone.
SHORT ESSAY (Answer any six)
6 X 5 = 30 Marks
4. Classify antitubercular agents with examples. Write the synthesis of p-aminosalicylic acid and
ethambutol.
5. Write a note on calcium channel blockers.
6. Write the SAR of quinolones.
7. Write a note on CADD and combitorial chemistry.
8. Classify antiarrthymic agents with example. Write the synthesis of warfarin
9. Write a note on prodrug.
10. Classify antihypertensive agents and give the synthesis of chlorpropamide.
11. Classify antineoplastic agents. Explain the mechanism of action of Chlorambucil
SHORT ANSWERS
10 X 2 = 20 Marks
12. Write the synthesis of diethyl carbamazine.
13. Write the synthesis of thiabendazole.
14. Write the structure and use of cycloserine and diloxanide furoate.
15. Write the structure and use of thienamycin and chloramphenicol.
16. Write the structure and use of macrolide antibiotic.
17. Write the synthesis of metronidazole.
18. Outline the synthesis of Tolnaftate
19. Mention two examples of plant products used as antineoplastic agents.
20. Write the structure of any two cephalosporin antibiotics.
21. Write the structure and use of L-thyroxine and methimazole.
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