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[KZ 813] OCTOBER 2011 Sub. Code: 3813
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
THIRD YEAR
PAPER I ? PHARMACOLOGY - II
Q.P. Code: 383813
Time: Three Hours
Maximum: 100 marks
Answer ALL questions in the same order.
I. Elaborate on :
Pages Time Marks
(Max.) (Max.) (Max.)
1. Classify diuretics according to their sites of action.
Explain the mechanism of action, pharmacological effects,
17 40 min. 20
therapeutic uses and adverse effects of loop diuretics.
2. Define signal transduction. Mention various kinase pathways.
Explain any two kinase pathways.
17 40 min. 20
II. Write notes on :
1. Clopidogrel.
4 10 min. 6
2. Receptors and therapeutic uses of vasopressin.
4 10 min. 6
3. Tetracycline.
4 10 min. 6
4. Amphotericin B.
4 10 min. 6
5. Nucleoside and nucleotide reverse transcriptase inhibitors.
4 10 min. 6
6. Monoclonal antibodies as immunosuppressants.
4 10 min. 6
7. Acute toxicity studies.
4 10 min. 6
8. Cell cycle regulators and modifiers.
4 10 min. 6
9. Histone deactyalses.
4 10 min. 6
10. Altered gene functions.
4 10 min. 6
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