Download Pharm D 3rd Year 2012 October 383813 Pharmacology II Question Paper

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[LB 813] OCTOBER 2012 Sub. Code: 3813

DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION

THIRD YEAR

PAPER I ? PHARMACOLOGY - II

Q.P. Code: 383813

Time: Three Hours











Maximum: 100 marks

Answer ALL questions in the same orde

I. Elaborate on :













Pages Time Marks



















(Max.) (Max.) (Max.)

1. a) Classify anti-neoplastic agents with examples.



17 40 min. 20

b) Write the mechanism of action, therapeutic uses of

methotrexate.

c) Discuss in detail about general toxicity of cytotoxic agents.



2. Define Protein. Discuss the mechanism and various



17 40 min. 20

steps involved in Protein synthesis.



II. Write notes on :

1. Give the category, mechanism of action and side effects

of Tacrolimus.













4 10 min. 6

2. Write a note on Mutation.











4 10 min. 6

3. Give the mechanism of action and side effects of co-trimoxazole. 4 10 min. 6

4. Give the therapeutic uses and mechanism of actions

of metronidazole and pyrimethamine.







4 10 min. 6

5. Write the therapeutic uses of ciprofloxacin.





4 10 min. 6

6. Write a note on Heparin antagonist.







4 10 min. 6

7. Write a note on haematinics.









4 10 min. 6

8. Classify diuretics with suitable example.

Give the therapeutic uses of thiazide diuretics.





4 10 min. 6

9. Write the mechanism of actions:









4 10 min. 6

(i) Acetazolamide (ii) Vasopressin (iii) Rifampicin.









10. Briefly explain (i) Translocation (ii) Tumour suppressor gene. 4 10 min. 6


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