Download Pharm D 3rd Year 2012 October 383813 Pharmacology II Question Paper

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[LB 813] OCTOBER 2012 Sub. Code: 3813

DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION

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THIRD YEAR

PAPER I - PHARMACOLOGY - 11

O.P. Code: 383813

Time: Three Hours Maximum: 100 marks

Answer ALL questions in the same order

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I. Elaborate on : Pages Time Marks

(Max.) (Max.) (Max.)

1. a) Classify anti-neoplastic agents with examples. 17 40 min. 20
   b) Write the mechanism of action, therapeutic uses of methotrexate.
   c) Discuss in detail about general toxicity of cytotoxic agents.

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2. Define Protein. Discuss the mechanism and various 17 40 min. 20
   steps involved in Protein synthesis.

II. Write notes on :

1. Give the category, mechanism of action and side effects of Tacrolimus. 4 10min. 6
2. Write a note on Mutation. 4 10min. 6

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3. Give the mechanism of action and side effects of co-trimoxazole. 4 10min. 6
4. Give the therapeutic uses and mechanism of actions of metronidazole and pyrimethamine. 4 10min. 6
5. Write the therapeutic uses of ciprofloxacin. 4 10min. 6
6. Write a note on Heparin antagonist. 4 10min. 6
7. Write a note on haematinics. 4 10min. 6

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8. Classify diuretics with suitable example.
   Give the therapeutic uses of thiazide diuretics. 4 10min. 6
9. Write the mechanism of actions: 4 10min. 6
   (1) Acetazolamide (ii) Vasopressin (iii) Rifampicin.
10. Briefly explain (i) Translocation (ii) Tumour suppressor gene. 4 10min. 6

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