Download Pharm D 3rd Year 2013 April 383817 Medicinal Chemistry Question Paper

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[LC 817] APRIL 2013 Sub. Code: 3817

DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION

THIRD YEAR

PAPER V ? MEDICINAL CHEMISTRY

Q.P. Code: 383817

Time: Three Hours











Maximum: 100 marks

Answer All questions

I. Elaborate on:

















(2 x 20 = 40)

1. Write the classification of Antivirals and explain in detail their chemistry, synthesis

of any 2 drugs with mechanism of action and examples. Explain on Prodrug concept.

2. Discuss on Computer aided drug design and modeling with an emphasis on its various

applications.

II. Write notes on:











(10 x 6 = 60)

1. Write the chemistry, structures and synthesis of any one drug under the category of

anticancer agents.

2. Discuss on anti protozoal agents.

3. Brief out on high ceiling diuretics

4. Write on Mechanism of action, toxicity and uses of Sulphonamides.

5. Brief out on antisence molecules.

6. Classify various anti-tubercular agents used for multiple drug resistant tuberculosis

and write their mechanism of action.

7. Give a short account on adrenocorticoids.

8. Write on oral hypoglycemic agents.

9. Discuss on antianginals.

10. Classify antimalarials and discuss on 4- amino quinolines.

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