[LD 813] OCTOBER 2013 Sub. Code: 3813
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
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THIRD YEAR
PAPER I - PHARMACOLOGY - 11
Q.P. Code: 383813
Time: Three Hours Maximum: 70 marks
Answer All questions
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-  Elaborate on: (2x20=40) - What are quinolones? Write the spectrum of activity, mechanism of action therapeutic uses and adverse reactions of ciprofloxacin.
- Classify anti cancer drugs with suitable examples. Write the mechanism of actions, therapeutic uses and adverse effects of paclitaxel. Add a note on hormones as anticancer drugs.
 
-  Write notes on: (10x 3 =30) - Write a note on fibrinolytic agents.
- Write a note on anti amoebic drugs.
- Write a note on loop diuretics.
- What are anti diuretic hormones? Give its therapeutic uses.
- Write a note on acute toxicity studies.
- What is DNA replication? Give its importance.
- What are the vectors used in gene transfer?
- Write a note on gene mapping.
-  What is mean by - Mutation
- Deletion
- Amplification?
 
- What are macromolecules? Give its functions.
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