Download Pharm D 3rd Year 2012 April 383813 Pharmacology II Question Paper

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[LA 813] APRIL 2012 Sub. Code: 3813

DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION

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THIRD YEAR

PAPER I - PHARMACOLOGY - II

Q.P. Code: 383813

Time: Three Hours Maximum: 100 marks

Answer ALL questions in the same order

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I. Elaborate on : Pages Time Marks
(Max.) (Max.) (Max.)

1. Define antibiotics. Explain the general mechanism of action of various antibacterial agents. Discuss the pharmacology of penicillins. (17 Pages, 40 min, 20 Marks)
2. Explain gene transcription and various factors that regulate transcription. (17 Pages, 40 min, 20 Marks)

II. Write notes on :

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1. Mechanism of action and drug interactions involving warfarin. (4 Pages, 10 min, 6 Marks)
2. Potassium-sparing diuretics. (4 Pages, 10 min, 6 Marks)
3. Aminoglycoside antibiotics. (4 Pages, 10 min, 6 Marks)
4. Classify anti leprotic drugs and discuss about dapsone. (4 Pages, 10 min, 6 Marks)
5. Calcineurin inhibitors. (4 Pages, 10 min, 6 Marks)

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6. Chronic toxicity studies. (4 Pages, 10 min, 6 Marks)
7. Ion channels. (4 Pages, 10 min, 6 Marks)
8. MAP kinase pathway. (4 Pages, 10 min, 6 Marks)
9. Biosensors. (4 Pages, 10 min, 6 Marks)
10. Gene therapy. (4 Pages, 10 min, 6 Marks)

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