[PHARMD 0122] JANUARY 2022 Sub. Code: 3823
(OCTOBER 2021 EXAM SESSION)
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PHARM ‘D’ AND PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATIONFOURTH YEAR
PAPER V - BIOPHARMACEUTICS AND PHARMACOKINETICS
O.P. Code : 383823
Time : Three hours Answer ALL Questions Maximum : 70 Marks
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- I. Elaborate on: (4 x 10 =40)
- Define Biotransformation. Explain the chemical pathways of drug biotransformation.
- Explain the various models of Pharmacokinetic analysis.
- Explain in detail about the factors causing non-linearity.
- Define Bioavailability. Explain the pharmacokinetic methods to estimate the bioavailability of drugs.
- II. Write notes on: (6 x 5 = 30)
- Mean residence time
- Kinetics of protein —drug binding
- Drug Accumulation
- Method of residuals in two compartment IV bolus administration
- Volume of Distribution.
- Non-renal routes of drug excretion
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