Download Pharm D 4th Year 2022 January Biopharmaceutics And Pharmacokinetics Question Paper

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[PHARMD 0122] JANUARY 2022 Sub. Code: 3823

(OCTOBER 2021 EXAM SESSION)



PHARM `D' AND PHARM. `D' (POST BACCALAUREATE) DEGREE EXAMINATION

FOURTH YEAR

PAPER V ? BIOPHARMACEUTICS AND PHARMACOKINETICS

Q.P. Code : 383823


Time : Three hours

Answer ALL Questions Maximum : 70 Marks


I. Elaborate on:

(4 x 10 = 40)



1. Define Biotransformation. Explain the chemical pathways of drug

biotransformation.

2. Explain the various models of Pharmacokinetic analysis.

3. Explain in detail about the factors causing non-linearity.

4. Define Bioavailability. Explain the pharmacokinetic methods to estimate the

bioavailability of drugs.



II. Write notes on:



(6 x 5 = 30)



1. Mean residence time

2. Kinetics of protein ?drug binding

3. Drug Accumulation

4. Method of residuals in two compartment IV bolus administration

5. Volume of Distribution.

6. Non-renal routes of drug excretion



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