Sub. Code: 3823
(OCTOBER 2020 EXAM SESSION)
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PHARM ‘D’ AND PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATION
FOURTH YEAR
PAPER V — BIOPHARMACEUTICS AND PHARMACOKINETICS
O.P. Code : 383823
Time : Three hours Maximum : 70 Marks
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- I. Elaborate on: (4 x 10 =40)
- Explain the various physiological barriers in the distribution of drugs.
- MRT for various pharmacokinetic models.
- Define Absorption. Explain in detail about in vitro drug dissolution testing models.
- Explain oral two compartment kinetics. Derive and compute Ka by using Loo - Riegelman method.
- II. Write notes on: (6x5=30)
- Urinary excretion studies.
- Discuss Latin square design in bioequivalent study.
- ONE compartmental - IV infusion administration
- Write a note on statistical moment theory.
- Factors affecting Bioavailability.
- Factors affecting renal excretion.
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